Nilgün IŞIKSAÇAN, Uğur KÖKTÜRK, Mehmet GÜL, Hüseyin Altuğ ÇAKMAK, Selahattin TÜREN, Aydın Rodi TOSU, Muhammet Hulusi SATILMISOĞLU, Muammer KARAKAYALI, Emre YILMAZ

Primer perkutan girişim uygulanan akut STEMI hastalarda başvuru D vitamini düzeyinin uzun dönem prognostik değeri

Amaç: Vitamin-D, insan vücudunda özellikle kardiyovasküler sistemin işlevi için çok önemlidir. Bu çalışmanın amacı, primer perkütan koroner girişim (PPCI) uygulanan akut ST-segment yükselmeli miyokard infarktüsünde (STEMI), hastane başvurusu sırasındaki D vitamini düzeyinin uzun dönem prognostik değerini araştırmaktı. Yöntemler: Bu prospektif çalışmada, eğitim ve araştırma hastanesine STEMI tanısı ile başvuran ve PPCI uygulanan ardışık 157 hasta alındı. Çalışma hastaları başvuru vitamin-D düzeylerine göre 2 gruba ayrıldı: Yüksek vitamin-D grubu (n = 80) ve düşük vitamin-D grubu (n = 77). Koroner arter hastalığının şiddeti SYNTAX skoru ile hesaplandı. Bulgular: Vitamin-D düzeyi ile SYNTAX skoru, serum glikozu ve cinsiyet arasında anlamlı negatif korelasyon vardı, fakat hemoglobin düzeyi ile pozitif korelasyon vardı. Kardiyovasküler mortalite, düşük vitamin-D grubunda, yüksek gruba göre anlamlı olarak daha yüksek bulundu (p

Assessment of long term prognostic value of admission vitamin D level in patients with acute STEMI undergoing primary percutaneous coronary intervention

Objective: Vitamin-D status is very important for optimal function of human body especially cardiovascular system. The aim of thisstudy was to investigate the long term prognostic value of admission vitamin D level in acute ST-segment elevation myocardialinfarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI).Methods: One hundred fifty seven consecutive patients, who were admitted to a training and research hospital with a diagnosis ofSTEMI and underwent PPCI, were recruited in this prospective study. The study patients were divided into 2 groups according totheir vitamin-D levels as follows: High vitamin-D group (n=80) and Low vitamin-D group (n=77). The severity of coronary arterydisease (CAD) was assessed with calculation of the SYNTAX score.Results: There were significant negative correlations between Vitamin-D level and SYNTAX score, serum glucose, and gender, but apositive correlation with hemoglobin level. Cardiovascular mortality was found to be significantly higher in the low vitamin-Dgroup as compared to the high group (p

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