Objective: This study aimed to evaluate the reliability and quality of videos on YouTube as an information resource about Kinesio taping (KT). Methods: We made a search on YouTube using the keyword "Kinesiotaping" on November 10, 2021. The popularity of first 200 videos evaluated with the video power Index (VPI), reliability with the modified DISCERN (M-DISCERN) score, and quality with the global quality score (GQS). Results: Of the 98 videos evaluated, 42(42.9%) were categorized as high-quality, 36(36.7%) as low-quality, and 20(20.4%) as moderate-quality. Significant positive correlations were observed between GQS, M-DISCERN, and VPI (p<0.001, for all). Number of views, number of views/days, number of likes, number of dislikes, duration of videos, and number of comments were significantly lower in low quality videos than those of moderate and high-quality videos(p<0.05). Conclusion: The quality of YouTube videos as an information source on KT were of moderate level. As the quality and reliability of the videos increase, their popularity also increases. Health professionals who use YouTube as informational material in KT applications should consider this situation.