Yusuf MADENDAĞ, Mefküre ERASLAN ŞAHİN, Erdem ŞAHİN, İlknur ÇÖL MADENDAĞ, Mehmet AK

Oral mikronize progesteronun ilk trimester tarama belirteçlerine ve yeni doğan sonuçlarına etkisi

Amaç: ilk trimester gebeliklerde kullanılan oral mikronize progesteronun (OMP), ilk trimester tarama belirteçleri olan; ense saydamlığı kalınlığı, anne serum beta-insan koryonik gonadotropin (β-hCG) ve gebelikle ilişkili plazma protein-A (PAPP-A) düzeylerine etki edip etmediğinin araştırılması amaçlandı. Ayrıca, OMP kullanan gebe kadınlarda yenidoğan sonuçlarını değerlendirmeyi amaçladık. Yöntemler: Bu çalışma Ocak 2015-Ağustos 2017 tarihleri arasında 1192 gebe kadın dahil olmak üzere retrospektif olarak yapıldı. Vücut kitle indeksi (VKİ), maternal ve gestasyonel yaş, anne serum PAPP-A ve serbest β-hCG düzeyleri, ense saydamlığı ve ölçümü baş-popo uzunluğu (CRL) ölçümü, fetal cinsiyet, fetal doğum ağırlığı, Apgar skoru 5.dakika

The effect of oral micronized progesterone on first trimester screening test markers and neonatal outcome

Objective: It was aimed to investigate whether or not nuchal translucency(NT) thickness, maternal serum free betahuman chorionic gonadotropin(β-hCG) and pregnancy-associated plasma protein-A(PAPP-A) levels may affected bythe use of oral micronized progesterone(OMP) in first trimester pregnancies. Also we aimed to evaluate pregnancyoutcome in pregnant women using OMP.Method: This study was performed retrospectively including 1192 pregnant women, between January 2015 andAugust 2017. Body mass index(BMI), maternal and gestational age, levels of maternal serum PAPP-A and free β-hCG,NT measurement and the crown–rump length(CRL), fetal sex, fetal birth weight, Apgar score 5thminute

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