Mehmet ERTÜRK, Özgür SÜRGİT, Ahmet Arif YALÇIN, Fatih UZUN, Özgür AKGÜL, Muhammet GÜRDOĞAN, İbrahim Faruk AKTÜRK, Ender ÖNER, Ali BİRANT, Abdurrahman EKSİK

Nötrofil/Lenfosit oranı ile yavaş koroner akım arasındaki ilişkinin incelenmesi

Amaç: Çalışmamızda yavaş koroner akım (SCF) ile nötrofil/lenfosit oranı (NLR) ve lökosit alt tipleri arasındaki ilişkiyi araştırmayı amaçladık. Yöntemler: Çalışmaya; koroner arter hastalığı şüphesiyle koroner anjiyografisi yapılan toplam 135 hasta alındı. Hastalar koroner anjiyografisi sonucuna göre üç gruba ayrıldı: yavaş koroner akım saptanan 45 hasta grup 1, en az bir koroner arterinde 50% ve üzerinde darlık saptanan 45 hasta grup 2 ve normal koroner arterlere sahip 45 kişi ise grup 3\'e (kontrol grubu) dahil edildi. Koroner yavaş akım tanısı her bir koroner arterin TIMI kare sayısı hesaplanarak kondu. Tüm hastalardan 12 saatlik açlık sonrası kan örnekleri alındı. NLR oranı tam kan sayımından faydalanılarak hesaplandı. Bulgular: Nötrofil/lenfosit oranı koroner arter hastalığına sahip olanlarda, yavaş koroner akım ve kontrol grubuna göre anlamlı olarak daha yüksekti (sırasıyla p=0,008 ve p

Anahtar Kelimeler:

Nötrofil/lenfosit oranı, lökosit alt tipleri, yavaş koroner akım, koroner arter hastalığı

The evaluation of relationship between neutrophil-to-lymphocyte ratio and slow coronary flow

Objective: The aim of this study was to investigate the correlations between leukocyte counts, the neutrophil-to-lymphocyte ratio (NLR), and slow coronary flow (SCF). Methods: We evaluated 135 patients undergoing coronary angiography (CAG) within coronary artery disease (CAD) indication. We divided patients into three groups according to the CAG findings. Group 1 consisted of 45 patients with an SCF pattern; group 2 consisted of 45 patients with at least 50% lumen narrowing in at least one epicardial coronary artery; and group 3 (control group) consisted of 45 patients with normal coronary arteries. The quantification of the coronary flow was assessed using the thrombolysis in myocardial infarction (TIMI) frame count method for each of the coronary arteries. Blood samples were collected from the patients after a 12 h overnight fasting. The NLR ratio was calculated from the automated complete blood count. Results: NLR in CAD was higher than in both the SCF and control groups (p=0.008, p

Keywords:

Neutrophil-to-lymphocyte ratio, leukocyte subtype, slow coronary flow, coronary artery disease,

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