Sedat MOTOR, Recep DOKUYUCU, Fatih SEFİL, M. Murat RİFAİOĞLU, ERHAN YENGİL, Kemal Türker ULUTAŞ, Ahmet Taner SÜMBÜL, Hatice RIZAOGLU, İhsan ÜSTÜN, Cumali GÖKÇE

Diabetes mellituslu hemodiyaliz hastalarında HbA1c ile kan glukozu düzeyleri arasındaki ilişki

Amaç: Bu çalışmada Diabetes mellitus (DM)lu, kronik böbrek yetmezliği olan ve diyalize giren hastalarda HbA1c düzeyleri ile kan glukozu düzeyleri arasındaki ilişkinin incelenmesi amaçlanmıştır. Yöntemler: 1 Ocak 2009-31 Temmuz 2010 tarihleri arasında, özel bir diyaliz merkezinde diyalize giren 131 (53 kadın, 78 erkek) hastanın aylık kan glukozu ve 3 aylık HbA1c sonuçları geriye dönük olarak incelendi. Bulgular: 131 olgunun yaş ortalaması 63,3±11,2 yıl (30- 91 yaş arası) idi. Bu olguların 53ü kadın (%40,5), 78i erkek (%59.5) idi. Kadınların yaş ortalaması 62,2±11,2 iken erkeklerin yaş ortalaması 64,1±11,2 idi. Kadınların ve erkeklerin ortalama glukoz değeri ile ortalama HbA1c de- ğeri arasında korelasyon vardı (Kadın: p

Relationship between Hba1c and blood glucose level in hemodialysis patients with diabetes mellitus

Objective: Within in the scope of this study, a research was aimed at the relationship between HbA1c markers and blood glucose levels with DM, chronic renal failure and receiving dialysis treatment. Methods: In this study, monthly glucose levels and quarterly HbA1c markers of 131 patients (53 female, 78 male) receiving dialysis treatment in a private dialysis center between January 1, 2009-July 31, 2010 were evaluated retrospectively. Results: The average age of 131 cases was 63.3±11.2 years (range, 30-91). Gender distribution of the cases: 53 female (40.5%), 78 male (59.5%). While the age average of the females was 62.2±11.2 and the males was 64.1±11.2. The average glucose level of the females and males have a correlation to average HbA1c (Female: p<0.001, r=0.761, Males: p<0.001, r=0.743). The average glucose level of the both case groups have a correlation to average HbA1c (p<0.001, r=0.755). While 32.8% of the examined HbA1c results were observed under the level 6,5%, and 67.2% of the examined results were observed above the level 6.5%. While 18.3% of the preprandial blood glucose levels were obtained under 126 mg/dl level, and 81.3% of the results were obtained above 126 mg/dl level. It has been observed that the mean blood glucose level has a correlation to average HbA1c level. Conclusion: The measurement of HbA1c and blood glucose (pre-prandial and postprandial) and the correlation between them, by virtue of the fact that, are vitally important in cardiovascular mortality and morbidity, monitor of DM for the dialysis patients with diabetic nephropathy.

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