Kahraman COŞANSU, Cagın Mustafa UREYEN, Harun KILIÇ, Bilgehan KARADAĞ, Ayca TURER CABBAR, Huseyin GUNDUZ, Rmazan AKDEMİR

New Uses of Platelet-Lymphocyte Ratio for Bleeding Risk Stratification in Patients with Nonvalvular Atrial Fibrillation: A Pilot Study

Objective: The primary aim of this study was to investigate the role of platelet-lymphocyte ratio (PLR) to predict bleedingrisk in nonvalvular atrial fibrillation (NVAF). Secondary aim was to determine the possible relation between PLR andthromboembolic and bleeding risk scores. Tertiary aim was to evaluate the predictive value of PLR for the patients in thetherapeutic international normalized ratio (INR) range.Method: PLR was calculated from the complete blood count of 228 patients who were under warfarin management forNVAF. The patients were called and it was questioned whether they had experienced the bleeding event within six monthsafter measurement of the PLR values.Correspondence/Yazışma Adresi: Kahraman Cosansu, Deparment of Cardiology, Sakarya University, Education and Research Hospital Sakarya, Turkey,54100 e-mail: kahraman141@gmail.comDOI: 10.5798/dicletip.705814Results: Bleeding event was observed in 48 patients after the PLR was calculated. It was found significantly correlationbetween PLR and CHA2DVAS2C (p

Non-Valvuler Atriyal Fibrilasyonu Olan Hastalarda Kanama Risk Sınıflandırılmasında Platelet-Lenfosit Oranının Yeni Kullanımları: Pilot Çalışma

Amaç: Bu çalışmanın birincil amacı, PLR'nın NVAF'da kanama riskini tahmin etmedeki rolünü araştırmaktı. İkincil amaç, PLR ile tromboembolik ve kanama riski skorları arasındaki olası ilişkiyi belirlemekti. Üçüncül amaç, terapötik INR aralığındaki hastalar için PLR'nin prediktif değerini değerlendirmekti. Yöntemler: PLR, non-valvüler AF nedeniyle warfarin tedavisi altında olan 228 hastanın tam kan sayımından hesaplandı. PLR değerlerinin ölçümünden altı ay sonra hastalara telefon edildi ve bu altı ay içinde herhangi bir kanama olayı yaşayıp yaşamadığı sorgulandı. Bulgular: PLR hesaplandıktan sonra 48 hastada kanama olayı gözlendi. PLR ile CHA2DVAS2C (p

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