Yasemin KARABULUT YUYUCU, Duygu KANKAYA, Gülşah KAYGUSUZ, Işınsu KUZU

Tdt positive small round cell tumor: Is this always lymphoblastic leukemia/lymphoma?

Merkel hücreli karsinom dağılmış kromatine sahip, dar sitoplazmalı, blastic görünümdemorfolojiye sahip derinin yüksek gradeli nöroendokrin tümörüdür. Terminal deoksinükleotidiltransferaz lenfoblastik lösemi lenfoma ve bazı akut myeloid lösemilerde timik T hücrelerindeneksprese olan bir DNA polimerazdır. Burada terminal deoksinükleotidil transferaz pozitif merkelhücreli karsinom olgusu sunulmaktadır.

Tdt p ozitif küçük yuvarlak hücreli tümör: Her zaman lenf oblastik lösemi/lenf oma mıdır?

Merkel cell carcinoma is a high-grade neuroendocrine carcinoma of the skin characterized by cellswith a blastic appearance, scanty cytoplasm, evenly distributed chromatin. Terminal deoxy- nucleotidyl transferase is a DNA polymerase expressed by thymic T cells lymphoblasticlymphoma/leukemia and some cases of acute myeloid leukemia. Herein, we report a case ofTerminal deoxy-nucleotidyl transferase positive small round cell tumor in consistent with Merkelcell carcinoma.

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