Serhat İÇAĞASIOĞLU, Fatih KILIÇLI, Fettah ACIBUCU, Bülent UYGUNGELEN, İbrahim GÜL, Ali Uğur USLU

Serum adiponectin level in hypertensive patients and its association with atherosclerotic risk factors

Amaç. Hipertansiyon aterosklerozun majör risk faktörlerindendir. Adiponektin başlıca beyazadipoz dokudan sentez edilmekte ve endotelyal hücreler ve makrofajlar üzerinde antiaterojenik veantiinflamatuar etkileri olduğu bilinmektedir. Yöntem. Çalışmaya 48i hipertansif 32 tanesinormotansif 80 birey alındı. Gruplar kendi arasında obez ve nonobez olarak ayrıldı. Bulgular.Hasta grubunun kontrol grubuna göre sistolik kanbasıncı, diastolik kanbasıncı, açlık kan şekeri,total kolesterol, trigliserit, low density lipoprotein-C, hs-CRP ve mikroalbuminüri değerleriistatistiksel olarak anlamlı yüksek, high density lipoprotein-C değerleri ise anlamlı düşük bulundu(p

Hip ertansif hastalarda serum adip onektin düzeyi ve ateroskleroz risk f aktörleri ile ilişkisi

Aim. Hypertension is one of the major risk factors for atherosclerosis. Adiponectin is mainlysynthesized by white adipose tissue; it is known to have anti-atherogenic and anti-inflammatoryeffects on endothelial cells and macrophages. Methods. A total of 80 individuals including 48hypertensive and 32 normotensive individuals were included in the study. Groups were separatedas obese and non-obese. Results. It was found out that the patient group had statistically highersystolic blood pressure, diastolic blood pressure, fasting plasma glucose, total cholesterol,triglyceride, low density lipoprotein, high sensitive C reactive protein and microalbuminuriavalues than the control group while high density lipoprotein values were significantly lower(p

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