Tülay AYSAL, Şener BARUT, Ünal ERKORKMAZ, Feyza YILDIZ AYTEKİN, Selçuk KILIÇ, Fazlı DEMİRTURK, Özgür GÜNAL

A preliminary report of relationship between abortion and Q fever in Central Black Sea Region Turkish woman

Amaç. Q ateşi Coxiella burnetii tarafından oluşturulan bir zoonozdur. Q ateşi gebe hayvanlarda vegebe kadınlarda abortusa neden olabilir. Biz bu çalışmamızda Q ateşi için endemik bir bölgede Qateşi seropozitifliği ve abortus arasındaki ilişkiyi araştırdık. Yöntem. Bu çalışma GaziosmanpaşaÜniversitesi Hastanesinde Mart 2012-Mayıs 2012 tarihleri arasında yürütüldü. Çalışmaya 18 yaşüzerinde toplam 100 kadın dahil edildi. Bunların 64ünün spontan abortus hikayesi pozitif (vakagrubu) iken 36sının hiç komplikasyonlu gebelik veya doğum hikayesi yoktu (kontrol grubu). Heriki grup yaşadıkları yer, altta yatan hastalıkları, çiflik hayvanı veya evcil hayvanlarla temas ve köyyaşantısı ile ilişki açısından karşılaştırıldı. Bulgular. Vaka grubunda Coxiella lgG seropozitifliği%15,6 çıkarken kontrol grubunda %11,1 olarak saptandı, bu fark istatistiksel olarak anlamlıdeğildi (p>0,05). Vaka grubu kontrol grubuyla karşılaştırıldığında köyde yaşama (p=0,012), çiftlikhayvanları ile temas [p=0,026; özellikle koyun (p=0,013)] veya evcil hayvanlarla temas (p=0,018)vaka grubunda anlamlı derecede daha yüksek saptandı. Tüm örnekler analiz edildiğinde CoxiellaIgG seropozitifliğini etkileyen en önemli değişken kırsal alanda yaşama veya kırsal yaşamla ilişkiliolma olarak bulundu (p=0,018). Sonuç. Çalışmanın sonucunda Q ateşi ile abortus arasında anlamlıbir ilişki bulunamadı. Bu çalışma bu konuyla ilgili ülkemizde yapılmış ilk çalışma olmakla birlikteçok merkezli ve yüksek örneklem sayılı çalışmalara ihtiyaç vardır.

Orta Karadeniz Bölgesi kadınlarında abortus ve Q ateşi arasındaki ilişkinin incelenmesi

Aim. Q fever, which is a zoonosis caused by Coxiella burnetii, may result in abortions in infectedanimals and pregnant women. In our study, we searched the association between Q fever serologyand abortion in a region where Q fever is endemic. Method. This study was conducted inGaziosmanpaşa University Hospital between March and May 2012. A total of 100 women, fromthese, 64 had a history of spontaneus abortion (cases) and 36 had live births with no complicatedobstetrics history or complicated partum (controls), enrolled in the study. Both groups werecompared according to where they live, underlying diseases, contact with farm animals or pets andvillage connectivity. Results. IgG seroprevalence of Coxiella in our study group with the historyof abortion was 15.6%, and 11.1% in the control group (p>0.05). When case and control groupswere compared, the frequency of inhabitants of the village (p=0.012), subjects who had contactwith farm animals [p=0.026, especially cattle (p=0.013)] or domestic animals (p=0.018) in casegroup were more common than the control group. When all the samples were analyzed, it was seenthat the only significant variable affecting Coxiella IgG seropositivity was residency in rural areaor visiting rural area (p=0.018). Conclusions. We have found that the relation between abortionand Q fever infection was not statistically significant. On this issue, multicenter studies whichhave the higher number of samples are needed in our country.

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