Senthil KUMAR, Azadeh BAGHERİ

Methicillin-Resistant Staphylococcus Aureus (MRSA) Carriage Certainly Poses a Risk in Pregnant Women

Amaç: Çalışmamızda MRSA taşıyıcısı hamile kadınlarda nazofaringeal durumunu belirlemek hedeflendi. MRSA için taradığımız 100 hamile kadından yalnızca 20 'sinde pozitif MRSA olduğu bulundu. Materyal ve Method: Nasal sürüntü örnekleri (her iki anterior burun deliğine ait) toplandı. Kanlı agar üzerine yayma yöntemi ile uygulandı. Agarda S. aureus ve MRSA varlığı ; oksasiline (oxacillin) hassas disk difüzyon methodu ile belirlendi. Bulgular: Bulgularımıza gore hamilelerin yaklaşık %30' unda literatürde yer alan yetişkinlerde görülen S. aureus koloni oranı ile tutarlı olarak S. aureus kolonileri gözlemlendi. Hindistan' ın Karnataka bölgesindeki hamilelerde MRSA kolonisi görülme oranı Ulusal sağlık ve beslenme inceleme ve araştırmalarının son dataları ile uyumlu olarak düşüktür. Sonuç: Hastaların 1 yıllık hastaneye alınma, cerrahi müdahale, dializ ve uzun sureli bakım hizmetleri, kalıcı kateter, deri altına yapılan tedavi müdahaleleri (trakeostomi tüpü, gastronomi tüpü, foley kateter ) gibi bilgiler kaydedildi. Bu problemin dışında pozitif MRSA' lı gebeler için geniş bir kontrol taraması da gerekir.

Methisilin Dirençli Staphylococcus Aureus (MRSA) Taşıyıcısı Hamile Kadınlardaki Risk Durumu

Purpose: The present study was aim to determine the incidence of nasopharyngeal carriage of MRSA in pregnant women. In this study 100 pregnant women screened for MRSA and only 20 of them found to be positive for MRSA. Material and Methods: Nasal swab samples were collected with sterile swabs from both anterior nares Swabs then were plated by streak plate method on Blood Agar Plate Isolates of S. aureus and MRSA identification by oxacillin susceptibility with the disc diffusion methods. Results: In our finding approximately 30% of pregnant women are colonized with S aureus is consistent with previous literature on the rate of S aureus colonization in adults. MRSA colonization among pregnant women in Karnataka state, India, remains low, which is consistent with recent data from the National Health and Nutrition Examination Survey. Conclusion: Patients with a history of hospitalization, surgery, dialysis, or residence in a long-term care facility within 1 year of enrollment, a permanent indwelling catheter or percutaneous medical device (eg, tracheostomy tube, gastrostomy tube, or Foley catheter) as well as pregnancy are known positive culture for MRSA and require an extensive check up to role out this problem.

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Lowy, Franklin D. "Staphylococcus aureus infections." New England Journal of Medicine. 1998;339:520-32.
Naimi, Timothy S., et al. "Comparison of community- and health care-associated methicillin-resistant Staphylococcus aureus infection." Jama. 2003;290:2976-84.
Centers for Disease Control and Prevention (CDC. "Methicillin-resistant Staphylococcus aureus skin or soft tissue infections in a state prison--Mississippi, 2000." MMWR. Morbidity and mortality weekly report. 2001;50:919.
Moran, Gregory J., et al. "Methicillin-resistant Staphylococcus aureus in community-acquired skin infections." 2005;11:928-30.
Enright, Mark C. "The evolution of a resistant pathogen-the case of MRSA." Current opinion in pharmacology. 2003;3:474-9.
Gordon, Rachel J., and Franklin D. Lowy. "Pathogenesis of methicillin-resistant Staphylococcus aureus infection." Clinical infectious diseases. 2008;5:350-9.
Palavecino, Elizabeth. "Community-acquired methicillin-resistant Staphylococcus aureus infections." 2004;24:403-18.
Gorwitz, Rachel J. "A review of community- associated methicillin-resistant Staphylococcus aureus skin and soft tissue infections." The Pediatric infectious disease journal. 2008;27:1-7.
Moazzez, Ashkan, et al. "Breast abscess bacteriologic features in the era of community- acquired methicillin-resistant Staphylococcus aureus epidemics." Archives of Surgery. 2007;142:881-4.
Beigi, Richard H., et al. "Epidemiologic and economic effect of methicillin-resistant Staphylococcus aureus in obstetrics." Obstetrics & Gynecology. 2009;113:983-91.
Lowy FD. Staphylococcus aureus infections. N Engl J Med. 1998;339:520-32.
Maguire GP, Arthur AD, Boustead PJ, et al. Emerging epidemic of community-acquired methicillin-resistant Staphylococcus aureus infection in the Northern Territory. Med J Aust. 1996;164:721- 3.
Centers for Disease Control and Prevention. Four pediatric deaths from community-acquired methicillin- resistant Staphylococcus aureus--Minnesota and North Dakota, 1997-1999. JAMA. 1999;282:1123-5.
Herold BC, Immergluck LC, Maranan MC, et al. Community-acquired methicillin-resistant Staphylococcus aureus in children with no identified predisposing risk. JAMA. 1998;279:593-8.
Gorak EJ, Yamada SM, Brown JD. Communityacquired methicillinresistant Staphylococcus aureus in hospitalized adults and children without known risk factors. Clin Infect Dis. 1999;29:797-800.
Abi-Hanna P, Frank AL, Quinn JP, et al. Clonal features of communityacquired methicillin-resistant Staphylococcus aureus in children. Clin Infect Dis. 2000;30:630-1.
Hussain FM, Boyle-Vavra S, Bethel CD, et al. Current trends in community- acquired methicillin- resistant Staphylococcus aureus at a tertiary care pediatric facility. Pediatr Infect Dis J. 2000;19:1163- 6.
Antioxidative and antibacterial activities of Indonesian Propolis Extracts Against Methicillin- Resistant Staphylococcus aureus (MRSA) in Vitro. Cukurova Medical Journal, 2014; 39:224-33.
Frank AL, Marcinak JF, Mangat PD, et al. Community-acquired and clindamycin-susceptible methicillin-resistant children. Pediatr Infect Dis J. 1999;18:993-1000.
Frank AL, Marcinak JF, Mangat PD, et al. Increase in communityacquired methicillin-resistant Staphylococcus aureus in children. Clin Infect Dis. 1999;29:935-6.