Vulvar Anjiyomiyofibroblastom: Bir Olgu Sunumu
Angimyofiblastomlar(AMFB), genital stromal tümörler içerisinde yer alan,nadir izlenen benign mezenkimal tümörlerdir. Genellikle orta-yaş bayanlarda görülüp, sıklıkla labium majörü daha az sıklıklada vajinayı etkileyebilmektedir. AMFB benzeri tümörler adı altında, nadiren erkekler de görülebilmektedir. Yerleşim yeri ve klinik prezentasyonu ile bartolin kistleri, alt genital tract lipomları veya nadiren de agresif anjiyomiksomalar ile karışabilmektedir. Vulvar kitle ile başvuran hastalarda, ön tanıda AMFB ler unutulmamalıdır. Tedavisi genellikle basit cerrahi eksizyondur.Bu olguda, bartolin kist yanlış ön tanısı ile medikal tedavi verilen AMFB olgusundan bahsedildi
Vulvar Angiomyofibroblastoma
Angiomyofibroblastoma (AMFB) is a rare seen mesenchymal tumor that is categorized as a genital stromal tumor. It is commonly seen in the middle-aged women usually affecting the labia majora and rarely the vagina. A variant called AMFB-like tumors are also rarely seen in male patients. AMFB with its clinical presentation and location can be wrongly diagnosed as an aggressive angiomyxomas, bartholin cyst or lower genital tract lipomas. In the patients who are applying because of the vulvar mass, AMFB should not be forgotten for the pre-diagnosis. The treatment is generally simple surgical excision.In this case, AMFB was reported with a wrongly pre-diagnosis as a bartholin cyst to which a medical treatment had been given.
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- Fletcher CD, Tsang WY, Fisher C, Lee KC, Chan JK. Angiomyofibroblastoma of the vulva. A benign neoplasm distinct from aggressive angiomyxoma. Am J Surg Pathol. 1992;16:373-82.
- McCluggage WG, White RG. Angiomyofibroblastoma of the vagina. J Clin Pathol. 2000;53:803.
- Ockner DM, Sayadi H, Swanson PE, Ritter JH, Wick MR. Genital angiomyofibroblastoma. Comparison with aggressive angiomyxoma and other myxoid neoplasms of skin and soft tissue. Am J Clin Pathol. 1997;107:36-44.
- Perko Z, Durdov MG, Druzijanic N, Kraljevic D, Juricic J. Giant perianal angiomyofibroblastoma-a case report. Coll Antropol. 2006;30:243-6.
- Park JH, Shin MK, Lee M, Park ST, Park SH, Kim HB.Angiomyofibroblastoma of the vulva: A case report with literature review. Case Reports in Clinical Medicine. 2013;2:221-4.
- Nielsen GP, Young RH, Dickersin GR, Rosenberg AE. Angiomyofibroblastoma of the vulva with sarcomatous transformation ("angiomyofibrosarcoma"). Am J Surg Pathol. 1997;21:1104-8.
- Nielsen GP, Young RH. Mesenchymal tumors and tumor-like lesions of the female genital tract: a selective review with emphasis on recently described entities. Int J Gynecol Pathol. 2001;20:105–27.
- Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA,Simonetti DW, Craig S, Marshak DR. Multilineage potential of adult human mesenchymal stem cells. Science. 1999;284:143-7.
- Kanda M, Sonoyama A, Hirano H, Kizaki T, Ohara N. Angiomyofibroblastoma of the vulva. Eur J Gynaecol Oncol. 2014;35:77-80.
- Ibnerasa SN, Yasmeen F, Shami N. Angiomyofibroblastoma of the vulva. J Coll Physicians Surg Pak. 2012;22:108-10.
- Uptodate.com [homepage on the internet] Disorders of bartholin gland; 2014 [updated 25 Nov 2013]. Available from: http://www.uptodate.com/contents/disorders-of- bartholin- gland?source=machineLearning&search=bartholin+c yst&selectedTitle=1%7E6§ionRank=1&anchor=H 2#H2