Üst gastrointestinal sistem endoskopisi yapılan hastalarda intestinal metaplazi ve Helikobakter pylori skorlarının karşılaştırılması

Amaç: Bu çalışmada dispeptik yakınmaları nedeniyle üst gastrointestinal system (GİS) endoskopisi yapılan hastalarda helicobacter pylori (HP) ile intestinal metaplazi (İM) arasındaki ilişkinin ortaya konulması amaçlanmıştır. Gereç ve Yönetim: Bu çalışmaya üst GİS endoskopisi yapılan 15-84 yaş arası hastalar dahil edildi. Hastaların demografik olarak yaş ve cinsiyetleri ile histopatolojik olarak İM ve HP skorları kaydedildi. Hastalar 15-49 yaş arası ve 50 yaş üstü olmak üzere sırasıyla Grup A ve Grup B olmak üzere iki gruba ayrıldı. İM ve HP skorları arasında çeşitli değişkenlere göre korelasyon olup olmadığı araştırıldı.Bulgular: Bu çalışmaya 15-84 yaş arası 200 hasta dahil edildi. Grup B’deki hastalarda IM görülme oranı istatiksel olarak anlamlı düzeyde yüksekti. HP negatif olan hastalarda ise; Grup B’deki hastalarda IM oranı, Grup A’ya göre anlamlı olarak yüksekti. Grup B’deki erkek hastalarda IMS hafif ve orta görülme oranı istatiksel olarak anlamlı düzeyde yüksekti.Sonuç: Literatürde HP pozitifliği ile İM gelişimi arasında anlamlı bir ilişki olduğunu gösteren çalışmaların yanısıra bu çalışmamızla uyumlu olarak HP pozitifliği ile İM gelişimi arasında anlamlı bir ilişki olmadığını bildiren çalışmalar da bulunmaktadır. Çalışmamızda İM gelişimi için en önemli risk faktörünün 50 yaş üzeri erkek cinsiyet olduğu sonucuna varılmıştır.

Anahtar Kelimeler:

Endoskopi, gastrointestinal sistem, intestinal metaplazi, helicobacter pylori

Comparison of intestinal metaplasia and Helicobacter pylori scores in patients undergoing upper gastrointestinal endoscopy

Purpose: The aim of this study is toreveal the relationship between Helicobacter pylori (HP) and intestinal metaplasia (IM) in patients with upper gastrointestinal endoscopy due to dissipative complaints.Materials and Methods: Patients aged 15-84 years who underwent upper gastrointestinal endoscopy were included in this study. Demographically age and sex of the patients and histopathologically IM and HP scores were recorded. Patients were divided into two groups, Group A and Group B, aged 15-49 and over 50 years old respectively. It was investigated whether there was correlation between IM and HP scores with regards to several variables.Results: This study included 200 patients aged 15-84 years. In Group B patients, IM incidence was significantly higher. In HP negative patients; IM rate in patients in Group B was significantly higher than Group A. In male patients in Group B, IMS mild to moderate incidence was statistically significantly higher.Conclusion: There are studies in the literature that show that there is a significant relationship between HP positivity and IM development, as well as studies that suggest that there is no significant relationship between HP positivity and IM development consistent with our study. The most important risk factor for the development of IM in our study was male sex above 50 years.

Keywords:

Endoscopy, gastrointestinal system, intestinal metaplasia, helicobacter pylori.,

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