Ufuk ÇAKIR, Duran YİLDİZ, Dilek KAHVECİOGLU, Emel OKULU, Serdar ALAN, Omer ERDEVE, Saadet ARSAN, Begum ATASAY

Obstetrik anestezi yöntemlerinin preterm bebeklerde gastrointestinal sistem fonksiyonu üzerine etkisi var mı?

Amaç: Prematüre bebeklerde gastrointestinal sistem (GİS) motilite problemlerinin nedeni multifaktöriyeldir ve intestinal immatürite en önemli faktördür. Sezaryen (C/S) ile doğum yapan prematüre bebeklerde epidural anestezi (EA) veya genel anestezinin (GA) GİS fonksiyonu ve erken neonatal morbidite üzerine etkisinin araştırılması amaçlanmıştır.Gereç ve Yöntem: Bu çalışma Ekim 2011 ile Nisan 2015 arasında tek bir yenidoğan yoğun bakım ünitesinde (YDYBÜ) yapılmıştır. Bu çalışmaya C/S ile doğan ≤32 hafta ve ≤1500 g pretermler dahil edildi. Anestezi yöntemi, demografik, klinik özellikler, ilk mekonyum geçiş zamanı, mekonyum obstrüksiyonu, dismotilite için ilaç kullanımı ve diğer preterm morbiditeleri değerlendirildi.Bulgular: Çalışma döneminde 364 preterm bebek kaydedildi. Dismotilite için ilaç kullanımı, ilk mekonyum geçiş zamanı ve mekonyum obstrüksiyonu oranı GA grubunda anlamlı olarak daha yüksekti.Sonuç: Bu literatürde anestezi yöntemlerinin preterm bebeklerde GİS motilitesi üzerine rolünü araştıra ilk çalışmadır. Doğum sırasındaki anestezi yöntemleri, preterm bebeklerde GİS fonksiyonu üzerinde etkili olabilir.

Anahtar Kelimeler:

anestezi metodu, mekonyum obstrüksiyonu, motilite, neonatal sonuç, preterm bebek

Do obstetric anesthesia methods have an impact on gastrointestinal system function in preterm infants?

Purpose: The reason for gastrointestinal system (GIS) motility problems in premature infants is multifactorial and intestinal immaturity is the most important contributing factor. To investigate the effect of epidural (EA) or general anesthesia (GA) on GIS function and early neonatal morbidity in preterm infants delivered by cesarean section (CS).Materials and Methods: This study was conducted in a single neonatal intensive care unit (NICU) between October 2011 and April 2015. Preterms ≤32 weeks and ≤1500g who were delivered by CS were enrolled in this study. Mode of anesthesia, demographic, clinical characteristics, first meconium passage time, meconium obstruction, use of drug for dysmotility and other preterm morbidities were evaluated. Results: Three hundred and sixty four preterm infants were enrolled during the study period. Use of drug for dysmotility, time to first meconium passage, and meconium obstruction rate, were significantly higher in the GA group. Conclusion: This was the first study in the literature that investigated the role of anesthesia methods, effect on preterm infant GIS motility. Anesthesia modalities during delivery may have an effect on GIS function in preterm infants.

Keywords:

Anesthesia method, meconium obstruction, motility, neonatal outcome, preterm infant,

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