Mesane kavitesini dolduran ileri yaş mesane tümörlerinde komplet rezeksiyon

Rezeke edilmesi mümkün görünmeyen yaygın mesane tümörlerinde sıklıkla uygulanan tedavi seçeneği radikal sistektomi olmaktadır. Ancak cerrahi öncesi sağlıklı evreleme yapabilmek, tümöre bağlı yakınmaları ortadan kaldırabilmek ve cerrahiyi kabul etmeyen ya da cerrahi tedavinin riskli olduğu olgularda alternatif tedavi seçeneklerini sunmak açısından komplet rezeksiyonun yapılması son derece önemlidir. Bu çalışmada ileri yaştaki mesane tümörlü iki olgunun neredeyse tüm mesane kavitesini dolduran tümörlerine uygulanan komplet rezeksiyon sonuçları aktarılmıştır.

Complete resection in old age bladder cancers filling bladder cavity

Radical cystectomy is often the treatment of choice in widespread bladder tumors that may not be possible to be resected. However, it is extremely important to perform a complete resection prior to surgery, to perform healthy staging, to remove complaints related to the tumor, and to offer alternative treatment options for patients who do not accept surgery or who are at risk for surgery. In this study, the results of complete resection of two old age patients with bladder cancer tumors filling all the bladder cavity were reported.

Keywords:

Bladder cancer, transurethral resection radical cystectomy,

PDF

___

1. Burger M, Catto JW, Dalbagni G, Grossman HB, Herr H, Karakiewicz P et al. Epidemiology and risk factors of urothelial bladder cancer. Eur Urol. 2013;63:234-41.
2. Schrier BP, Hollander MP, van Rhijn BW, Kiemeney LA, Witjes JA. Prognosis of muscle invasive bladder cancer: difference between primary and progressive tumours and implications for therapy. Eur Urol. 2004;45:292-6.
3. Sylvester RJ, van der Meijden AP, Oosterlinck W, Witjes JA, Bouffioux C, Denis L et al. Predicting recurrence and progression in individual patients with stage Ta, T1 bladder cancer using EORTC risk tables: a combined analysis of 2596 patients from seven EORTC trials. Eur Urol. 2006;49:465-6.
4. Kulkarni GS, Hakenberg OW, Gschwend JE, Thalmann G, Kassouf W, Kamat A et al. An updated critical analysis of the treatment strategy for mewly diagnosed high-grade T1(previously T1G3) bladder cancer. Eur Urol. 2010;57:60-70.
5. Bohle A, Jocham D, Bock PR. Intravesical bacillus Calmette-Guerin versus mitomycin C for superficial bladder cancer: a formal metaanalysis of comparative studies on recurrence and toxicity. J Urol. 2003;169:90-5.
6. Babjuk M, Oosterlinck W, Sylvester R, Kaasinen E, Böhle A, Palou-Redorta J et al. EAU Guidelines on non-muscle-invasive urothelial carcinoma of the bladder. Eur Urol. 2008;54:303-14.
7. Van Der Meijden A, Sylvester R, Collette L, Bono A, Ten Kate F. The role and impact of pathology review on stage and grade assessment of stages Ta and T1 bladder tumors: a combined analysis of 5 European Organization for Research and Treatment of Cancer Trials. J Urol. 2000;164:1533-7.
8. Grimm MO, Steinhoff C, Simon X, Spiegelhalder P, Ackermann R, Vogeli TA. Effect of routine repeat transurethral resection for superficial bladder cancer: a long term observational study. J Urol 2003;170:433-7.
9. Divrik RT, Şahin AF, Yıldırım Ü, Altok M, Zorlu F. Impact of routine second transurethral resection on the long-term outcome of patients with newly diagnosed pT1 urothelial carcinoma with respect to recurrence, progression rate, and diseasespecific survival: a prospective randomised clinical trial. Eur Urol 2010;58:185-90.
10. Zurkirchen MA, Sulster T, Gaspert A and Hauri D. Second transurethral reseciton of superficial transitional cell carcinoma of the bladder: a must even for experienced urologist. Urol Int. 2004;72:99-102.
11. Soria F, Moschini M, Korn S, Shariat SF. How to optimally manage elderly bladder cancer patients? Transl Androl Urol. 2016;5:683-91.
12. Batur AF, Sözen S. Yüksek riskli kasa invaze olmayan mesane kanserinde erken sistektomi mi yoksa mesane koruyucu tedavi mi tercih edelim? Üroonkoloji Bülteni. 2014;13:93-8.
13. Froehner M, Brausi MA, Herr HW, et al. Complications following radical cystectomy for bladder cancer in the elderly. Eur Urol. 2009;56:443-54.
14. Schiffmann J, Gandaglia G, Larcher A et al. Contemporary 90-day mortality rates after radical cystectomy in the elderly. Eur J Surg Oncol. 2014;40:1738-45