Antalya’da kolorektal kanser insidans ve sağkalım hızları, 2002–2016: topluma dayalı bir kayıt çalışması

Amaç: Bu çalışma, Antalya İl Sağlık Müdürlüğü Kanser Kayıt Merkezi’nin 2002–2016 yılları arasını kapsayan verileri kullanarak ileri yaştaki kolorektal kanser tanılı hastaların insidans ve sağkalım hızlarını incelemeyi amaçlamıştır. Gereç ve Yöntem: Antalya İl Sağlık Müdürlüğü bünyesinde aktif olarak sahadan veri toplayan topluma dayalı Kanser Kayıt Merkezi kayıtları kullanılarak, kolorektal kanser tanılı vakaların insidansları ile sağkalım hızları hesaplanmıştır. Bulgular: Antalya’da 2002 – 2016 arasında genel insidans kadınlarda yüzbinde 19,5 ve erkeklerde yüzbinde 11,6 olarak bulunmuştur. Tanı konduğu sırada vakaların %75,0’i localize evreyi geçmiş durumda, %25,0’i uzak yayılım göstermektedir. Genel sağkalım süresi 6,0 ± 0,1 yıl olarak saptanmış ve 65 yaş öncesinde tanı almış olanlarda rölatif olarak daha uzun yaşam süresi olduğu görülmüştür. Rektum yerine kolonda yerleşmiş kanserlerin ile orta düzeyde diferansiye olanlar daha yüksek oranda 10-yıllık kümülatif sağkalım süresine sahiptir. Kolorektal kanser tanısını 65 yaşından önce almış olanların, daha sonra tanı almış olanlara göre 1,25 kez, cerrahi yolla tedavi edilenlerin, diğer yöntemlerle tedavi uygulananlara göre 7,53 kez daha iyi prognoza sahip oldukları görülmüştür. Sonuç: Çalışma sonuçlarımıza göre, Antalya'da tanı anında kolorektal kanserin tespit edilen evresi ileri evredir ve bu nedenle sağkalım süresini uzatan cerrahi tedavi şansı daha az olmaktadır. Tanı sırasındaki tedavi türü prognozunu etkilediğinden erken tanı önem kazanmaktadır.

Incidence of colorectal cancer and survival rates of older patients in Turkey, 2002 – 2016: a population - based registry study

Purpose: This study aimed to investigate the incidence and survival rates of advanced colorectal cancer patients using data from 2002 to 2016 of the Antalya Provincial Health Directorate Cancer Registry Center. Materials and Methods: The incidence and survival rates of cases diagnosed with colorectal cancer were calculated by using the community-based Cancer Registry Center records that actively collect data from the field within the Antalya Provincial Health Directorate. Results: In Antalya, between 2002 and 2016, the overall incidence was found to be 19.5 per hundred thousand for women and 11.6 per hundred thousand for men. At the time of diagnosis, 75.0% of the cases have passed the localized phase, and 25.0% show distant spread. The overall survival time was 6.0 ± 0.1 years, and patients aged < 65 years old at diagnosis had a relatively longer survival time. The colon cancer and moderately differentiated groups had a higher 10-year cumulative survival. Patients aged < 65 years old at diagnosis had a better prognosis (1.25 times) than older patients, and patients treated surgically had a better prognosis (7.53 times) than those treated with other treatments. Conclusion: According to our study results, the stage of colorectal cancer is more advanced at the time of diagnosis in Antalya, and therefore there is less chance of surgical treatment that extends the survival time more. Early diagnosis gains importance as the type of treatment during diagnosis affects its prognosis.

Keywords:

colorectal cancer colorectal cancer incidence, colorectal cancer survival rate,

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