Zehra AYDIN, Habip ALMIŞ, Ceyda CİLASUN, İbrahim Hakan BUCAK, Mehmet TURĞUT

Rotavirüs-Pozitif ve Rotavirüs-Negatif İshali Olan Çocukların Değerlendirilmesi

Amaç: Rotavirüs, çocuklarda en sık görülen ve elektrolit düzensizliği, şiddetli dehidratasyon, hipovolemik şok ve ölümle sonuçlanabilen akut gastroenterit nedenidir. Kesin tanı için geliştirilmiş serolojik yöntemler mevcut olsa da bu yöntemlere ulaşmak her zaman kolay olmayabilir. Bu çalışma rotavirüs tanısına yardımcı olan parametreleri değerlendirmeyi amaçlamaktadır. Gereç ve Yöntemler: Akut gastroenterit nedeniyle hastanemize başvuran 1 ay-18 yaş arası 1539 çocuğu retrospektif olarak inceledik. Hastalar rotavirüs pozitif ve rotavirüs negatif olarak iki gruba ayrıldı. RV-pozitif grupta 745 hasta ve RV-negatif grupta 794 hasta vardı. Bulgular: Ortalama RBC (p=0,005), Hb (p<0,001), Htc (p<0,001), MCV (p<0,001), nötrofil (p=0,001), platelet lenfosit oranı (p=0,003), nötrofil lenfosit oranı (p<0,001), eozinofil lenfosit oranı (p<0,001) seviyeleri RV-pozitif grupta anlamlı olarak daha düşüktü. Ortalama platelet düzeyi (p=0,005) ve ortalama lenfosit düzeyi (p<0,001) RV-pozitif grupta anlamlı olarak daha yüksekti. Sonuç: Rotavirüs gastroenteritinde birçok hematolojik parametre etkilenmiştir. RBC, Hb, Htc, MCV, ortalama trombosit düzeyi, ortalama nötrofil düzeyi, ortalama lenfosit düzeyi, trombosit/lenfosit oranı, nötrofil/lenfosit oranı, eozinofil/lenfosit oranı ve rotavirüs gastroenteriti için destekleyici olabilir

Anahtar Kelimeler:

Rotavirüs, Gastroenterit, Çocuk

Evaluation of Children With Rotavirus Positive And Rotavirus Negative Diarrhea

Objective: Rotavirus is the most frequent cause of infectious acute gastroenteritis in children and may result in electrolyte imbalance, severe dehydration, hypovolemic shock, and death. Even though improved serological methods for definitive diagnosis exist, these methods may not always be easy to reach. This study aims to evaluate the parameters that help the diagnosis of rotavirus gastroenteritis. Material and Methods: We retrospectively reviewed 1,539 children aged 1 month to 18 years who had been admitted to our hospital for acute gastroenteritis. Patients were divided into two groups: rotavirus positive and rotavirus negative. There were 745 patients in the RV-positive group and 794 patients in the RV-negative group. Results: The mean RBC (p=0.005), Hb (p<0.001), Htc (p<0.001), MCV (p<0.001), neutrophil (p=0.001), PLR (p=0.003), NLR (p<0.001), and ELR (p<0.001) levels were significantly lower in the RV-positive group. The mean PLT level (p=0.005) and the mean lymphocyte level (p<0.001) were significantly higher in the RV-positive group. Conclusion: Several hematological parameters were influenced in rotavirus gastroenteritis. RBC, Hb, Htc, MCV, the mean platelet level, the mean neutrophil level, the mean lymphocyte level, platelet /lymphocyte ratio, neutrophil/lymphocyte ratio, and the eosinophil/lymphocyte ratio could be supportive for rotavirus gastroenteritis.

Keywords:

Rotavirus, Gastroenteritis, Child,

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