Ayşe KILIÇ, İsmail YILDIZ, Rukiye EKER ÖMEROĞLU, Emin ÜNÜVAR, Talat CANTEZ

Pasif Sigara İçiciliğinin Çocuklarda Aterosklerotik Risk Faktörlerine Etkisi

Amaç: Çevresel sigara dumanının karotis arter intimal medial kalınlık ölçümlerine, kan lipid, lipoprotein düzeyleri ve kan basıncı üzerine etkisini ortaya koymak. Yöntemler: On dört-15 yaş grubuna giren ve evde kronik olarak pasif sigara dumanına maruz kalan 20 kız 20 erkek vakada karotis arter intimal medial kalınlığı, serum total kolesterol, LDL-C, HDL-C, VIDL-C, trigliserid düzeyleri ve kan basınçları ölçülerek aynı yaş grubundan 20 kız ve 20 erkekten oluşan kontrol grubuyla karşılaştırıldı. Bulgular: Pasif sigara dumanına maruz kalan grupta karotis arter intimal medial kalınlık ölçüm sonuçları, serum ortalama total kolesterol ve LDL-C düzeyleri anlamlı derecede daha yüksek, serum HDL-C düzeyleri anlamlı derecede düşük bulundu. Vakaların tümünde açlık kan glikoz düzeyleri normal sınırlarda bulundu. Pasif sigara dumanına maruz kalan grubun ortalama hem sistolik hem de diastolik kan basıncı değerleri anlamlı derecede yüksek bulundu. Ejeksiyon fraksiyon düzeylerinde ise anlamlı bir farklılık saptanmadı. Sonuç: Pasif sigara içiciliği karotis aterosklerozunda önemli bir risk faktörü olabilir

Anahtar Kelimeler:

Pasif sigara dumanı maruziyeti, ateroskleroz, karotis arter intimal medial kalınlığı, pasif sigara içiciliği

Passive Smoking as a Risk Factor for Atherosclerotic Changes

Objective: The aim of this study was to investigate the effect of passive smoking on carotid artery intimal medial thickness, blood lipid levels, lipoprotein levels and blood pressure. Methods: This descriptive study was carried out on 40 adolescents 20 girls and 20 boys aged 14-15 years who were identified as passive smokers at home and 40 adolescents 20 girls and 20 boys as the control group. Carotid artery intimal medial thickness, serum total cholesterol, LDL-C, HDL-C, VLDL-C, triglyceride levels and blood pressures were measured. Results: Carotid artery intimal medial thickness measurement, serum total cholesterol and LDL-C levels were significantly higher and serum HDL-C levels were significantly lower among passive smokers. Fasting blood glucose levels were normal in all cases. The mean systolic and diastolic blood pressure values of passive smokers group were significantly higher than those of control group. There was no difference in ejection fraction levels. Conclusion: Passive smoking may be an important risk factor for carotid atherosclerosis.

Keywords:

Passive exposure of tobacco smoke, atherosclerosis, carotid artery intimal medial thickness, passive smoking,

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