Asemptomatik perinatal sitomegalovirus infeksiyonunun neden olduğu infantil trombositopeni vakası

Tüm vücutta yaygın peteşiyal döküntü nedeniyle getirilen, üç aylık erkek hastada trombositopeni ile birlikte sitomegalovirus (CMV) spesifik IgM pozitifliği saptandı. Perinatal CMV infeksiyonu tanısı konulan hastaya uygun destekleyici tedavi yanında 400 mg/kg/gün dozunda beş gün intravenöz immunoglobulin tedavisi uygulandı. Hastanın trombositleri tedavinin beşinci gününden itibaren artmaya başladı ve 10. günde tam olarak düzeldi (>150x109/L). Bu vaka, nadir de olsa, sitomegalovirus infeksiyonunun sistemik bulgular olmadan, sadece trombositopeni ile ortaya çıkabileceğini göstermesi bakımından ilginç bulunup sunulmuştur.

Anahtar Kelimeler:

Süt çocuğu, yenidoğan, Sitomegalovirüs enfeksiyonları, Trombositopeni, İmmunoglobulin M

A case with thrombocytopenia secondary to a perinatal cytomegalovirus infection

Perinatal cytomegalovirus (CMV) infection was diagnosed in a 3-month-old male patient who was admitted with generalized petechiae on his body and diagnosed as perinatal cytomegalovirus infection with positivite cytomegalovirus specific IgM antibody and thrombocytopenia. He was given supportive therapy and additional intravenous immune globulin 400 mg/kg/day for five days. His thrombocytes began to increase on the 5th day of therapy and complete recovery was seen on the 10th day of the treatment. This interesting case was reported because CMV infection presented without systemic manifestations and with only thrombocytopenia.

Keywords:

Infant, Newborn, Cytomegalovirus Infections, Thrombocytopenia, Immunoglobulin M,

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