Coriandrum Sativum ve Foeniculum Vulgare Sulu Ekstrelerinin İn Vitro Antimikrobiyal Aktivite Değerlendirilmesi

Bu çalışma Coriandrum sativum ve Foeniculum vulgare sulu ekstrelerinin antimikrobiyal aktivitesini değerlendirmek üzere tasarlanmıştır. Ekstrelerin antimikrobiyal aktivitesi beş bakteri suşu ve iki mantar suşuna karşı agar kuyu difüzyon metodu ve MİK (minimum inhibitör konsantrasyon) değerleri kullanılarak test edilmiştir. Sonuçlar, sulu C. sativum ve F. vulgare ekstrelerinin test edilen tüm mikroorganizmalara karşı antibakteriyel ve antifungal aktiviteye sahip olduğunu, Nystatin'in ise C.cladosporides'e karşı herhangi bir etki göstermediğini göstermiştir. F. vulgare ve C. sativum aktiviterlerinde MİK değerleri aralığı, 0.7 ile 6.2 mg/mL olarak tespit edilmiştir. Bu nedenle sonuçlar, bu bitki ekstrelerinin antimikrobiyal bileşikler içerdiğini önermektedir ve böylelikle gelecekte insan mikrobiyal hastalıkları için yeni antimikrobiyal ajanlar olarak kullanılabilecektir.

Evaluation of in-vitro antimicrobial activity of Coriandrum sativum and Foeniculum vulgare aqueous extracts

The present study has been designated to evaluate the antimicrobial activity of Coriandrum sativum and Foeniculum vulgare aqueous extracts. The antimicrobial activity of the extracts against five bacterial strains and two fungal strains were tested by using agar well diffusion method and minimal inhibitory concentration MIC values. Results showed that aqueous extracts of C. sativum and F. vulgare had antibacterial and antifungal effects against all the tested microorganisms, wherease Nystatin failed to show any effect against C.cladosporides. The range of MIC values was 0.7 to 6.2 mg/mL in the F. vulgare and C. sativum treatments. Therefore, results suggest that these extracts contain antimicrobial compounds that can be used in the future as antimicrobial agents in the new drugs for human microbial diseases.

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