Metabolic Parameters in Patients with Adrenal Insidentaloma

Metabolic Parameters in Patients with Adrenal Insidentaloma

ABSTRACT Aim: Our aim is to determine the metabolic state in patients with incidental adrenal mass. Material and Methods: 67 patients in whom functional tests about adrenal incidental mass were assessed in University of Necmettin Erbakan, Faculty of Medicine, Department of Endocrinology and Metabolism, were admitted to the study. Results: Of these 67 patients, 34 were male and 33 were female. Mean age was 57.1±12, mean body mass index was 29.1±6 kg/m2. In patients enrolled to the study; cushing s syndrome, pheochromocytoma, primary hyperaldosteronism tests were performed. Functional adrenal mass was detected in 8 patients (6 pheochromocytoma, 1 cushing s syndrome, 1 primary hyperaldosteronism). Impaired fasting glucose or type 2 diabetes were identified in 38 patients. Mean glucose was 127.6±18 mg/dL in all patients. Mean glucose in patients with functional and non-functional mass were 117.2±32 mg/dL and 129±62 mg/dL respectively. Mean systolic blood pressure was 125±18 mmHg, and diastolic blood pressure was 77±10.9 mmHg in all patients. Mean systolic pressure was 135±10.4 mmHg in patients with functional mass and 124±19 mmHg in patients with non-functional mass. Mean triglyceride was 157.5 ± 83 mg/dL (normal

___

  • 1. Carrol TB, Aron DC, Findling JW, Tyrell JB. Glukokortikoidler ve adrenal androjenler, Greenspantemal Ve Klinik Endokrinoloji, çev ed:Tütüncü NB, Güneş Kitabevi, Ankara.2013; 285-328.
  • 2. Midorikawa S, Sanada H, Hashimoto S, Suzuki T, Watanabe T. The improvement of insulin resistance in patients with adrenal incidentalomas by surgical resection. Clinical Endocrinology. 2001;54(6):797–804.
  • 3. Emral R, Uysal AR, Asik M, Gullu S, Corapcioglu D, Tonyukuk V et al. Prevalence of subclinical Cushing’s syndrome in 70 patients with adrenal incidentaloma: clinical, biochemical and surgical outcomes. Endocrine Journal. 2003.;50(4):399-408.
  • 4. Bernini G, Moretti A, Iacconi P, Miccoli P, Nami R, Lucani B et al. Anthropometric, haemodynamic, humoral and hormonal evaluation in patients with incidental adrenocortical adenomas before and after surgery. European Journal of Endocrinology. 2003;148(2): 213–219.
  • 5. Tsuiki M, Tanabe A, Takagi S, Naruse M, Takano K. nonfunctionWorld J Surg Cardiovascular risks and their long-term clinical outcome in patients with subclinical Cushing’s syndrome. Endocrine Journal. 2008;55(4):737–745.
  • 6. Chiodini I, Morelli V, Salcuni AS, Eller Vainicher C, Torlontano M, Coletti F et al. Beneficial metabolic effects of prompt surgical treatment in patients with an adrenal incidentaloma causing biochemical hypercortisolism. Journal of Clinical Endocrinology and Metabolism. 2010;95(6):2736– 2645.
  • 7. Mantero F, Terzolo M, Arnaldi G, et al. A Survey on Adrenal Incidentaloma in Italy. J Clin Endocrinol Metab. 2000;85(2): 637-644
  • 8. Terzolo M, Pia A, Ali A, et al. Adrenal Incidentaloma: A New Cause of the Metabolic Syndrome. J Clin Endocrinol Metab. 2002;87(3): 998-1003
  • 9. Tauchmanova L, Rossi R, Biondi B, et al. Patients with subclinical Cushing’s syndrome due to adrenal adenoma have increased cardiovasculer risk. J Clin Endocrinol Metab. 2002;87(11):4872-4878
  • 10. Muscogiuri G1, Sorice GP, Prioletta A, Mezza T, Cipolla C, Salomone E, Giaccari A, Pontecorvi A, Della Casa S. The size of adrenal incidentalomas correlates with insulin resistance. Is there a cause-effect relationship? Clin Endocrinol (Oxf). 2011;74(3):300-5.
  • 11. Erbil Y, Ozbey N, Barbaros U, Unalp HR, Salmaslioglu A, Ozarmagan S. Cardiovascular risk in patients with nonfunctional adrenal incidentaloma: myth or reality? World J Surg. 2009;33(10):2099-105.
Bozok Tıp Dergisi-Cover
  • ISSN: 2146-4006
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2015
  • Yayıncı: Bozok Üniversitesi
Sayıdaki Diğer Makaleler

KONTAKT DERMATİTLİ OLGULARDA YAMA TESTİ SONUÇLARININ DEĞERLENDİRİLMESİ

Asena Çiğdem DOĞRAMACI, Özlem EKİZ, Emine Nur RİFAİOĞLU, Bilge BÜLBÜL ŞEN, Tuğba ŞEN

DERİN VEN TROMBOZUNDA TOTAL KOLESTEROL VE TRİGLİSERİD SEVİYELERİNİN ARAŞTIRILMASININ ÖNEMİ

Meral EKİM, Hasan EKİM, Yunus Keser YILMAZ, Zeynep Tuğba ÖZDEMİr

PRİMER İŞİTSEL NÖROPATİ: VAKA SUNUMU

Mustafa DİLEK, Veysel YURTTAŞ, Tuğçe ŞİMŞEK, Sevil Bilir GÖKSUGÜR, Murat ŞEREFLİCAN, Fatih RÜZGAR

İZOTERMİK HİPERKALEMİK KAN KARDİYOPLEJİSİNİN MYOKARD KORUNMASINDA ÖNEMİ

Meral EKİM, Yunus Keser YILMAZ, Hasan EKİM

NÖROFİBROMATOZİS TİP 1'DE KALP TUTULUMU

Zehra KARATAŞ, Sıddıka HALICIOĞLU, Zehra GÖKSÜGÜR BİLİR, Mervan BEKTAŞ, Emine ÇAKIR DEMİRBAŞ, Nadir GÖKSÜGÜR

Metabolic Parameters in Patients with Adrenal Insidentaloma

Mustafa KULAKSIZOĞLU, Elif TURAN, Feridun KARAKURT, Ahmet KAYA

SEMPTOMATİK HALKA ŞEKİLLİ LATERAL MENİSKUS: VAKA SUNUMU

Sinan KARAOĞLU, Fatih KARAARSLAN

HİPERTANSİF HASTALARDA NABIZ BASINCI ARALIĞI İLE SOL VENTRİKÜL DİASTOLİK FONKSİYON İLİŞKİSİ

Ali Rıza ERBAY, İsa ARDAHANLI, Mehmet Ali DERYA, Onur AKGÜN, Hüseyin EDE

İNTRAOPERATİF KONSÜLTASYON İLE TANI ALAN SAFRA KESESİNİN PRİMER SKUAMÖZ HÜCRELİ KARSİNOMU

Müzeyyen ASTARCI, Gülzade ÖZYALVAÇLI, Gülan AKTAŞ, Hüsna BAYRAKDAR

İNME, HİPERTANSİYON VE BEYİN YARIKÜRESİ ARASINDAKİ İLİŞKİ

Nermin TANIK, Asuman ÇELİKBİLEK, Savaş SARIKAYA, Yurdanur AKYÜZ