Sıçanlarda Ihlamur (Tilia platyphyllos Scop) İnfüzyonunun İmmün Sistem Üzerine Etkilerinin Araştırılması

Çay olarak tüketilen en yaygın bitkilerden biri olan ıhlamur (Tilia platyphyllos Scop) bitki çiçek özellikle soğukkış aylarında yoğun şekilde tüketilmektedir. Halk arasında, güçlü sakinleştirici etkisinin olduğu, iltihaplanmayıazalttığı, tansiyonun düşürülmesine destek olduğu, bağışıklık sistemini güçlendirdiği kabul edilmektedir.Fakat ıhlamur çayının kullanım süresi, sıklığı ve dozuna bağlı olarak canlılar üzerinde nasıl bir etkiye sahipolduğunu gösteren araştırmalar sınırlıdır. Bu çalışmada, sıçanlar her grupta altı adet sıçan bulunan dört grubaayrıldı. Grup 1 [(kontrol grubu) (sadece musluk suyu)], grup 2 [(%20 EtOH) (musluk suyu+%20 etil alkolkarışımı)], grup 3 [(LF) (musluk suyu+ %2 ıhlamur çiçek infüzyon karışımı)], grup 4 [( EtOH +LF) (etil alkol+%2 ıhlamur çiçe k infüzyonu)] . Günlük hazırlanan içme suları ve karışımları 50 gün süreyle sıçanlara verildi. Buçalışmada, EtOH'un immünotoksik etkilerine karşı LF infüzyonunun iyileştirici etkilerini ortaya koymak içinsıçanlarda immün sistem biyobelirteçlerinden adenozin deaminaz (ADA) ve miyeloperoksidaz (MPO)aktiviteleri üzerine olası etkilerinin ölçülmesi amaçlanmıştır. Sonuç olarak, analiz dokularında ADA ve MPOaktivitesinin kontrol gruplarına göre önemli ölçüde arttığı belirlendi (p

Investigation of the Effects of Linden (Tilia platyphyllos Scop) Infusion on Immune System in Rats

One of the most common plants consumed as tea, the linden (Tilia platyphyllos Scop) plant flowers are consumed extensively during the cold winter months. It is considered that it has a strong sedative effect, reduces inflammation, supports tension reduction, and strengthens the immune system. However, there are limited studies showing how linden tea has an effect on living beings due to the duration, frequency and dose of lime tea. In this study, rats were divided into four groups of six rats in each group. Group 1 [(control group) (only tap water was given)], group 2 [(20% EtOH) (mixed water + 20% ethyl alcohol mixture)], group 3 [(LF) (tap water + 2% linden flower infusion mixture was given)] , group 4 [(EtOH + LF) (ethyl alcohol + 2% linden flower infusion)]. Daily prepared drinking water and mixtures were given to rats for 50 days. The aim of this study was to determine the possible effects of adenosine deaminase (ADA) and myeloperoxidase (MPO) activities on immune system biomarkers in rats to demonstrate the therapeutic effects of LF infusion against the immunotoxic effects of EtOH. As a result, ADA and MPO activity were significantly increased in the control tissues compared to the control groups (p

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