PERİODONTAL HASTALIKTA YAŞLILIK İLE KEMİK MARKIRLARININ İLİŞKİSİ

Yaşlanmanın insan organizması üzerindeki etkisi bütün organ ve dokularda izlenebilir. Yaşlanmanın biyolojisinde çeşitli fizyolojik, immünolojik, psikolojik ve çevresel faktörlerin etkili olduğunu göstermektedir. Periodontal hastalığın aktivitesinin izlenmesinde en önemli faktörlerden biride alveol kemik kaybıdır. Periodontal hastalık aktivitesinin biyokimyasal olarak değerlendirilmesinde de kemik yapım ve yıkım markırları önem taşımaktadır. Son yıllardaki çalışmalar, kemik yapım ve yıkım markırlarının enflamatuar komponentlerinin mevcudiyeti hipotezinden hareketle, periodontal hastalık ve yaşlılık ilişkisine odaklanan sınırlı sayıda çalışmada incelenmiştir. Bu derlemede kemik yapım ve yıkım markırlarının periodontal hastalık ve yaşlılıkla olan ilişkisi özetlenmiştir.

Anahtar Kelimeler:

yaşlılık, kemik yapım-yıkım markırı

RELATIONSHIP BETWEEN AGEING AND BONE TURNOVER MARKERS IN PERIODONTAL DISEASE

Ageing effect could see every tissue and organ. In ageing biology many physiological, immunological, psychological and environmental factors have been shown to be effective. One of the most important factors of periodontal disease activity is alveolar bone loss. Biochemical evolutions of periodontal disease activity bone turnover markers are crucial. Limited studies in recent years are focus on inflammatory disease and bone turnover markers. In this review we summarized about bone turnover biomarkers between periodontal disease and ageing.

Keywords:

ageing, bone turnover markers,

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