Sepsis-Değişiklikler Sepsis– Current Changes
Sepsis her türlü mikroorganizma ve/veya onların ürünleri ile ortayaçıkabilen kompleks inflamatuar bir hastalıktır. Sepsis ve septik şoktanımı, en son 2001 de yapılmış, epidemiyoloji, patobiyoloji ve sepsisyönetimindeki değişikliklerin yeniden gözden geçirilmesi gerekmiştir.Sepsis 3.0’ın erken tanıma, farkındalık ve zamanında sepsis yönetimisağlayacağı düşünülmektedir.
___
- [1] Michael D. Howell, MD, MPH, Andrew M. Davis, MD, MPH
Management of Sepsis and Septic Shock JAMA.
2017;317(8):847-848. doi:10.1001/jama.2017.0131
[2] Lakshmikanth CL, Jacob SP, Chaithra VH, de Castro-Faria-
Neto HC, Marathe GK. Sepsis: in search of cure.Inflamm
Res. 2016 Aug;65(8):587-602. doi: 10.1007/s00011-016-0937-y.
[3] Dellinger RP, Levy MM, Rhodes A, et al. Surviving Sepsis
Campaign Guidelines Committee Including the Pediatric
Subgroup. Surviving Sepsis Campaign: international
guidelines for management of severe sepsis and septic shock:
2012. Crit Care Med. 2013; 41(2):580–637.
[4] Funk DJ1, Parrillo JE, Kumar A.Sepsis and septic shock: a
history.Crit Care Clin. 2009 Jan;25(1):83-101, viii. doi: 10.1016/j.
ccc.2008.12.003.
[5] Bone RC, Balk RA, Cerra FB, et al. American College of Chest
Physicians/Society of Critical Care Medicine Consensus
Conference: definitions for sepsis and organ failure and
guidelines for the use of innovative therapies in sepsis. Crit Care
Med. 1992; 20(6):864–874.
[6] Levy MM, Fink MP, Marshall JC, et al. International Sepsis
Definitions Conference. 2001 SCCM/ESICM/ACCP/ATS/SIS
International Sepsis Definitions Conference. Intensive Care Med.
2003; 29(4):530–538.
[7] Singer M, Deutschman CS2, Seymour CW, Shankar-
Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche
JD, Coopersmith CM, Hotchkiss RS, Levy MM, Marshall
JC, Martin GS, Opal SM, Rubenfeld GD, van der Poll T, Vincent
JL, Angus DC. [12] The Third International Consensus
Definitions for Sepsis and Septic Shock (Sepsis-3).JAMA. 2016
Feb 23;315(8):801-10. doi: 10.1001/jama.2016.0287.
[8] Vincent J-L, Opal SM, Marshall JC, Tracey KJ. Sepsis
definitions: time for change. Lancet. 2013; 381(9868):774–775.
[PubMed: 23472921]
http://adelaideemergencyphysicians.com/2016/02/sepsis-3-0-andthe-
quick-sofa/
9] Mickiewicz B, Thompson GC, Blackwood J, Jenne CN, Winston
BW, Vogel HJ, Joffe AR; Alberta Sepsis Network. Development
of metabolic and inflammatory mediator biomarker phenotyping
for early diagnosis and triage of pediatric sepsis. Crit Care. 2015
Sep 9;19:320. doi: 10.1186/s13054-015-1026-2
[10] Pierrakos C, Vincent JL.Sepsis biomarkers: a review.
Crit Care. 2010;14(1):R15. doi: 10.1186/cc8872. Epub 2010 Feb 9.
[12] Thompson GC, Macias CG. Recognition
and Management of Sepsis in Children: Practice Patterns in
the Emergency Department..J Emerg Med. 2015
Oct;49(4):391-9. doi: 10.1016/j.jemermed.2015.03.012.