İshalli neonatal buzağılarda strong (metabolik) ion asidozisin tedavisine genel bakış

Neonatal buzağı ishallerine bir veya birden daha fazla etken neden olabilir. İshalli buzağılarda strong ion (metabolic) asidozis yaygın olarak gözükür. Strong ion asidozisle ilişkili klinik semptomlar spesifik olmayıp belirsizdir. Fakat strong ion asidozisin şiddetinin tahmininde buzağının yaşı göz önünde bulundurulabilir. Çünkü aynı klinik bulgulara sahip buzağılardan yaşamının ilk haftasındaki buzağılar, bir haftalıktan büyük buzağılara kıyasla daha az asidemiktir. Ayrıca emme refleksi ile baz açığı değeri arasında yakın ilişki bulunmaktadır. Buzağılarda ishalle ilişkili ölümün azaltılmasında en önemli faktörlerden biri uygun oral veya intravenöz sıvıların kullanılmasıdır. Sistemik metabolik asidozisisi düzeltmek için uygun alkalize ajanların kullanılması gerekmektedir. Bikarbonat kandaki H+ iyonu ile direk reaksiyona girdiğinden dolayı, bikarbonat içeren intravenöz sıvılar şiddetli asideminin düzeltilmesinde oldukça etkilidir. Laktatlı ringer veya asetatlı ringer solüsyonlar ise hafiforta derecede metabolik asidozisi düzeltmede tercih edilir.

Anahtar Kelimeler:

Buzağı, ishal, strong (metabolik asidozis) ion, dehidrasyon

General overview to treatment of strong ion (metabolic) acidosis in neonatal calves with diarrhea

Diarrhea in neonatal calves is due to one or more causes. Strong ion (metabolic) acidosis is common in diarrheic calves. Clinical signs associated with metabolic acidosis are vague and nonspecific. However, the calf’s age can be used to predict the severity of metabolic acidosis, because one weak old diarrheic calves are less acidemic than older calves despite they have similar clinical signs. Moreover, the suckling reflex is closely associated with base excess parameters. One of the most important factors for decreasing mortality rates associated with diarrhea in calves is parenteral and oral administration of appropriately formulated electrolyte solutions. Inclusion of an alkalinizing agent is required to correct systemic metabolic acidosis. Bicarbonatecontaining fluids are more effective at rapidly correcting severe acidemia, since bicarbonate reacts directly with H+ ions. Lactated Ringers solution or Acetated Ringers solutions can be used to correct mild to moderate acidosis.

Keywords:

Calf, diarrhea, strong (metabolic) ion acidosis, dehydration,

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