Yılmaz Niyazi YAZMAN, İbrahim İYİGÜN, Naci ŞEN

İdiyopatik hipoparatiroidizm ve epilepsi

Bu yazıda epilepsi tanısı ile takip edilmekte-ve difenilhidantoin tedavisi almakta iken hipokalsemi, çok düşük parathormon düzeyleri ve bilgisayarlı tomografide bazal gangliyonlarda bilateral simetrik kalsifikasyonların saptandığı bir idiyopatik hipoparatiroidizm vakası sunulmuş ve idiyopatik hipoparatiroidizmin etyopatogenezi, klinik görünüm ve tedavisi literatür bilgilen eşliğinde gözden geçirilmiştir.

Idiopathic hypoparathyroidism and epilepsy

In this paper, one case of idiopathic hypoparathyroidism with the initial diagnosis of epilepsy under diphenylhydantoin treatment had hypoealcemia, very low parathyroid hormone level, bilateral symmetric calcification in the basal ganglia on the computerized tomography was presented and clinical presentation and treatment of idiopathic hypoparathyroidism related to recent literature were reviewed.

PDF

___

1. Schipper HM, Abrams GM. Other endocrinopathies and the nervous system. In: Aminoff MJ (ed). Neurology and General Medicine. 2Ih ed., New York: Livingstone, 1995;20:383-400
2. Friedman JH, Chiucchini I, Tucci JR.Idiopathic hypoparathyroidism with extensive brain calcification and persistent neurologic dysfunction. Neurology 1987; 37:307-309
3. Abe S, Tajo K, Ichida K, et al. A rare case of idiopathic hypoparathyroidism with varied neurological manifestations. Intern Med 1996; 35:129-134
4. Morgante L, Vita G, Meduri M, at al. Fahr's syndrome: local inflammatory factors in the pathogenesis of calcification. J Neurol 1986; 233:19-22
5. Vakaet A, Rubens R, de Reuck J, vender Eecken H. Intracranial bilateral symmetrical calcification on CT-scanning: a case report and a review of the literature. Clin Neurol Neurosurg 1985; 87:103-111
6. Duran MJ, Borst GC 3rd, Osburne RC, Eil C. Concurrent renal hypomagnesemia and hypoparathyroidism with normal parathormone responsiveness. Am J Med 1984; 76:151-154
7. McLeod DR, Hanley DA, McArthur RG. Autosomal dominant hypoparathyroidism with intracranial calcification outside the basal ganglia. Am J Med Genet 1989;32:32-35
8. Kistler HJ. Idiopathic hypoparathyroidism-a rare disaese ? Schweiz Med Wochenschr 1996; 126:718-722