Serap SATIŞ, Alparslan YETİŞGİN, Kudret Cem KARAYOL

Yaş Gruplarına Göre Kemik Mineral Yoğunluğu, Kalsiyum, Fosfor, Alkalen Fosfataz, Paratiroid Hormon Düzeyleri

Bu çalışmanın amacı, total lomber1-lomber 4 ve femur boynu kemik mineral yoğunluğu, kalsiyum, fosfor, alkalen fosfataz, paratroid hormon gibi kemik sağlığını rutin değerlendirdiğimiz parametrelerin yaşa göre karşılaştırılmasıdır. Gereç-Yöntem: Dual Enerji X-ray Absorbsiometri ile kemik mineral yoğunluğu ölçümü yapılmış olan, 40 yaş üstü 713 hasta retrospektif olarak tarandı. Sekonder osteoporozu olan hastalar çalışma dışı bırakıldı. Çalışmaya 106 hasta dahil edildi. Hastalar; Grup 1;40-49 yaş, Grup 2;50-59 yaş, Grup 3;60-69 yaş ve Grup 4;70-79 yaş olarak dört gruba ayrıldı. Hastaların Lomber 1-Lomber 4 total ve femur boynu Kemik mineral yoğunluğu, kalsiyum, fosfor, alkalen fosfataz, paratroid hormon ve D vitamini değerleri hasta dosyalarında çıkarılarak kayıt altına alındı. Gruplar arasında karşılaştırma yapıldı. Bulgular: Kalsiyum, lomber 1-lomber 4 total ve femur boynu kemik mineral yoğunluğunda gruplar arasında istatistiksel anlamlı bulgular gözlenirken; ileri yaş hastalarda kalsiyum da yüksek gözlendi; D vitamini, fosfor, alkalen fosfataz, paratroid hormon değerlerinde, gruplar arasında fark saptanmadı. Fakat, tüm gruplarda, vitamin D seviyeleri normal değerin altındaydı. Tartışma: D vitamini düzeyleri tüm gruplarda düşüktü. Yaşlı yetişkinlerde düşük kemik mineral yoğunluğu ve yüksek kalsiyum seviyeleri gözlemlemiştir. Sonuç: İleri yaş olan hastalarda beklenildiği şekilde kemik mineral yoğunluğu daha düşük bulunmuştur. Ayrıca kalsiyum değeri bu grupta yüksek gözlendi; bu sonucun ileri yaş hastaların immobilizasyonuna bağlı olabileceği düşünülebilir.

Anahtar Kelimeler:

Kemik Mineral Yoğunluğu, Kalsiyum, Fosfor, Alkalen Fosfataz, Paratroid Hormon

Bone Mineral Density, Calcium, Phosphorus, Alkaline Phosphatase, Parathyroid Hormone Levels in Age Groups

Aim: The aim of this study is to compare the levels of lumbar 1 - lumbar 4 total, femoral neck bone mineral density, calcium, phosphorus, alkaline phosphatase, parathyroid hormone and vitamin D values which are routinely used to evaluate bone health by age. Methods: We retrospectively reviewed 713 patients over the age of 40 who underwent dual-energy x-ray absorptiometry. Patients with secondary osteoporosis were excluded. A total of 106 patients were included in the study. The patients were divided into four groups according to their ages: Group 1; 11 patients, 40-49 years, Group 2; 42 patients, 50-59 years, Group 3; 34 patients, 60-69 years and Group 4; 10 patients, 70-79 years. Lumbar 1–lumbar 4 total and femoral neck bone mineral density, calcium, phosphorus, alkaline phosphatase, parathyroid hormone and vitamin D values were extracted from the patient files and recorded. We examined the relationships between the groups. Results: Calcium, lumbar 1 - lumbar 4 total and femoral neck bone mineral density were statistically significant between the groups; the highest calcium value was observed among group 4 patients, and the comparison between the groups was statistically significant. There was no difference, in vitamin D, phosphorus, alkaline phosphatase and parathyroid hormone levels between the groups. Vitamin D levels were low in all groups. Discussion: Vitamin D levels were low in all groups. Older adults also observed low bone mineral density (BMD) and high calcium levels. Conclusion: Lower bone mineral density in patients with advanced age was as expected. In addition, a high calcium value was observed in this group; this result may be thought to be due to the immobilization of elderly patients.

Keywords:

Bone Mıneral Density, Calcium, Phosphorus, Alkaline Phosphatase, Parathyroid Hormone,

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