Ventilatör İlişkili Diyafram Disfonksiyonu: Patogenez, Tanı veYeni Tedaviler

Diyafram, ana inspiryum kasıdır ve optimal solunum için diyafram fonksiyonunun hayati önemi vardır. Diyafram yetmezliği, çeşitli sistemik nöromüsküler hastalıklara eşlik edebilir ve ölüm riskini artırır. Ayrıca, mekanik ventilasyon (MV) uygulaması, ventilatör ilişkili diyafram disfonksiyonuna (VİDD) yol açabilir. Son zamanlarda, VİDD’nin, kritik hastaların çoğunda olup, ventilatörden ayrılma zorlukları ile ilişkili olduğu gösterilmiştir. Bu derleme, VİDD patogenezini, tanısını ve tedavisini özetlemektedir.

Ventilator-Induced Diaphragmatic Dysfunction: Pathogenesis, Diagnosis and New Therapeutics

The diaphragm is the main inspiratory muscle and the diaphragm function is of vital importance for optimalbreathing. Diaphragm dysfunction may accompany various systemic neuromuscular diseases and increase the risk ofdeath. Furthermore, the use of mechanical ventilation (MV) therapy leads to ventilator-induced diaphragmdysfunction (VIDD). Recently, VIDD has been shown to be associated with the severity of weaning from theventilator in most critical patients. This review summarizes the pathogenesis, diagnosis and treatment of VIDD.

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