Hemodiyaliz Hastalarında Serebrovasküler Olaylar

İnme dünya çapında morbidite ve mortalitenin önde gelen nedenlerinden biridir. İskemik ve hemorajik olarak iki gruba ayrılır ve diyabet, hipertansiyon, sigara ve obezite gibi kardiyovasküler hastalıklar ile benzer risk faktörlerine sahiptir. Kronik böbrek hastalığı da sıklığı her geçen gün artan ve geleneksel risk faktörleri dışında, üremik toksinler, anemi, trombosit disfonksiyonu, hipervolemi, malnütriyon-inflamasyon, artmış oksidatif stres gibi kendine has risk faktörleri olan bir hastalıktır. Diyalize giren hasta sayısı ülkemizde her yıl %10 oranında artmaktadır ve bu hasta grubunda inme, kronik böbrek hastalığının tüm aşamalarında genel populasyona göre 2-10 kat fazla görülmektedir. Bu derlemede, inmenin risk faktörleri ve alt tipleri dahil olmak üzere kronik böbrek hastaları ve diyaliz hastalarında inmeye genel bir bakış sunulmaktadır.

Cerebrovascular Events in Hemodialysis Patients

Stroke is one of the leading causes of morbidity and mortality worldwide. It could be ischemic or hemorrhagic and has similar risk factors as cardiovascular diseases such as diabetes, hypertension, smoking and obesity. Chronic kidney disease has its own risk factors such as uremic toxins, anemia, platelet dysfunction, hypervolemia, malnutrition-increased inflammation, increased oxidative stress, in addition to traditional risk factors. The number of patients undergoing dialysis increases every year by 10% in our country and, stroke is seen as 2-10 times more in all stages of chronic kidney disease compared to the general population in this patient group. An overview of stroke is presented here including the risk factors and subtypes of stroke in chronic kidney disease and dialysis patients.

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