From the point of view of a gastroenterologist: Is the ulcer malign, or benign?

From the point of view of a gastroenterologist: Is the ulcer malign, or benign?

Aim: To evaluate the opinion of the physician and the necessity of repeat endoscopy to be performed in the prediction of malignancyin patients with endoscopic detection of gastric ulcer.Materials and Methods: Patients who underwent endoscopy for any reason between 01.01.2019-01.10.2019 and who had gastriculcer were included in the study. The physician who performed the endoscopy was asked to report their opinion about the ulcerendoscopically. By comparing the biopsy results taken from the ulcer and the opinion of the physician who performed the endoscopy,the accuracy of the doctor's prediction about the ulcer was evaluated.Results: A total of 411 patients, 186 women (45.3%), 225 men (54.7%), were included in the study. In 126 (30.7%) of the 411patients who participated in the study, ulcers were malignant. 106 (84.1%) of these patients were also considered to have definitivemalignancy by the physician as a result of endoscopy. physician opinion was suspicious in 17 (13.5%) of them. Although only 3(2.4%) patients were considered to have benign ulcers, the pathology result was malignant ulcer. Considering all patients, sensitivitywas calculated as 84.1%; specificity 98.5%; positive predictive value 96.3%; negative predictive value 93.3%; AUC 0.914; and p

___

  • 1. Yeo SH, Yang CH. Peptic Ulcer Disease Associated with Helicobacter pylori Infection. Korean J Gastroenterol 2016;67:289-99.
  • 2. Stolte M, Seitter V, Müller H. Improvement in the quality of the endoscopic/bioptic diagnosis of gastric ulcers between 1990 and 1997 - An analysis of 1,658 patients. Z Gastroenterol 2001;39:349-55.
  • 3. Maniatis AG, Eisen GM, Brazer SR. Endoscopic discrimination of gastric ulcers. J Clin Gastroenterol 1997;24:203-6.
  • 4. Bustamante M, Devesa F, Borghol A, et al. Accuracy of the initial endoscopic diagnosis in the discrimination of gastric ulcers: is endoscopic follow-up study always needed? J Clin Gastroenterol 2002;35:25-8.
  • 5. Pruitt RE, Truss CD. Endoscopy, gastric ulcer, and gastric cancer. Follow-up endoscopy for all gastric ulcers? Dig Dis Sci 1993;38:284-8.
  • 6. Tatsuta M, Iishi H, Okuda S, et al. Prospective evaluation of diagnostic accuracy of gastrofiberscopic biopsy in diagnosis of gastric cancer. Cancer 1989;63:1415-20.
  • 7. Llanos O, Guzman S, Duarte I. Accuracy of the first endoscopic procedure in the differential diagnosis of gastric lesions. Ann Surg. 1982;195:224-6.
  • 8. Amorena ME, Borda CF, Martínez-Peñuela Virseda JM, et al. Analysis of the clinical benefits and costeffectiveness of performing a systematic second-look gastroscopy in benign gastric ulcer. Gastroenterol Hepatol 2009;32:2-8.
  • 9. Dover F, Ipek S. Malignancy risk of gastric ulcers: could it be higher than the expected values? Hepatogastroenterology. 2003;50:312-4.
  • 10. Gielisse EAR, Kuyvenhoven JP. Follow-up endoscopy for benign-appearing gastric ulcers has no additive value in detecting malignancy: It is time to individualise surveillance endoscopy. Gastric Cancer 2015;18:803- 9.
  • 11. Griffin SM, Bowrey DJ, Allum WH. Upper gastrointestinal surgeons comment on NICE dyspepsia guidelines . Br Med J 2005;330:308-9.
  • 12. Banerjee S, Cash BD, Dominitz JA, et al. The role of endoscopy in the management of patients with peptic ulcer disease. Gastrointest Endosc 2010;71:663-8.
  • 13. Saini SD, Eisen G, Mattek N, et al. Utilization of upper endoscopy for surveillance of gastric ulcers in the United States. Am J Gastroenterol 2008;103:1920-5.
  • 14. Xu CY, Shen JG, Shen JY, et al. Ulcer size as a novel indicator marker is correlated with prognosis of ulcerative gastric cancer. Dig Surg 2009;26:312-6.
  • 15. Selcukbiricik F, Tural D, Bilici A, et al. Clinicopathological features and localization of gastric cancers and their effects on survival in Turkey. Asian Pac J Cancer Prev 2013;14:553-6.
Annals of Medical Research-Cover
  • Yayın Aralığı: 12
  • Yayıncı: İnönü Üniversitesi Tıp Fakültesi
Sayıdaki Diğer Makaleler

Retrospective evaluation of anesthesia and surgery methods in proximal hypospadias cases

Serpil SANCAR, Derya KARASU, Esra ÖZÇAKIR, Mete KAYA, Ümran KARACA, Şeyda Efsun ÖZGÜNAY, Şermin EMİNOĞLU

Intensive care nurses’ attitudes toward the “dying with dignity” principles and affecting factors

Hakime ASLAN, Mehmet DÜNDAR

Prevalence and characteristics of foramen huschke: Cone beam computed tomography study

Oğuzhan DEMİREL, Aslıhan AKBULUT

Microorganisms isolated from external ear cultures and their antimicrobial susceptibility in patients with chronic suppurative otitis media: A six years experience

Mustafa Koray BALCI, Tuba MUDERRİS, Rahim ÖZDEMİR, Süreyya GÜL YURTSEVER, Selçuk KAYA

Effects of laparoscopy and laparotomy on stress and hemodynamics in experimental sepsis model in rats

Mustafa Gökhan ÜNSAL, Eyüp Murat YILMAZ, Erdem Barış CARTI, Çiğdem YENİŞEY, Ulaş Utku ŞEKERCİ

Is abdominal wall hemorrhage an avoidable complication of robotic radical prostatectomy?

Erdem KOÇ, Bahri GÖK

Neonatal COVID-19 case from Turkey; a Case report of neonatal

İsmail Kürşad GÖKÇE, Mehmet Fatih DEVECİ, Ramazan ÖZDEMİR

Dermatofibrosarcoma protuberans: An unusual case of breast

Kazım GEMİCİ, Ramazan GÜNDOĞDU

How can clinically-safe and effective Platelet Rich Plasma (PRP) be obtained in a laboratory?

Recep Onur KARABACAK, Latife ATASOY KARAKAŞ, Derya DENİZ ERCAN, Esra KARABAY, Seyhan GÜMÜŞLÜ

Foreign bodies in the external auditory canal: A single center experience

Mustafa ALTINTAŞ