Vezikoüreteral Reflüde Antibiyotik Profilaksisi
Primer vezikoüreteral reflü (VUR) mesane disfonksiyonu ve üriner sistem enfeksiyonu riskinde artÖLla yakÖndan iliLkili olan çocukluk ça?Öna ait sÖk ve önemli bir patolojidir. VUR tanÖsÖ alan çocuklarÖn ço?unda kendili?inden geçse de, bir kÖsmÖnda reflü nefropatisi, hipertansiyon, idrar yolu enfeksiyonu ve mesane disfonksiyonu gibi olumsuz sonuçlar do?urabilmektedir. Antibi- yotik profilaksisi VUR'lu hastalarda ilk tedavi seçene?i olarak kabul edilirken son çalÖLmalara bakÖldÖ?Önda kesin bir görüL birli?i olmadÖ?Ö izlenmektedir. Bu derlemede primer VUR'de anti- biyotik profilaksisine güncel yaklaLÖmlar güncel kÖlavuzlar eLli?inde de?erlendirilmiLtir
Antibiotic Prophylaxis in Vesicoureteral Reflux
Vesicoureteral reflux (VUR) which is associated with bladder dysfunction and increased risk of urinary tract infection (UTI), is common and important urinary system abnormality seen inchildren. Although VUR spontaneously resolves in most of the cases, it might lead to severecomplications including reflux nephropathy, hypertension, UTI and bladder dysfunction. Thecontinuous antibiotic prophylaxis (CAP) in the management of VUR is first choice of therapy.However, controversy exists on CAP in the current studies and some questions have not been properly answered yet. In this paper the recent trends of CAP in VUR is reviewed under current guidelines.
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