Hesna BEKTAŞ, Orhan DENİZ, Gönül VURAL, Şadiye TEMEL

Evaluation of Patients with Cerebral Venous Sinus Thrombosis

inmenin yaygın olmayan formudur. Etiyolojide çok sayıda neden saptanmıştır Çalışmamızın amacı sinus ven trombozu nedeniyle kliniğimizde takip edilmiş hastaları retrospektif olarak incelemek ve altta yatan etiyolojileri, yaş ve cinsiyet dağılımını, klinik ve görüntüleme bulgularını tartışmaktır. Gereç ve Yöntem: Ocak 2005-Ocak 2015 tarihleri arasında Nöroloji servisinde yatarak etiyolojik araştırılması yapılan 68 hastanın retrospektif olarak hastane kayıtları ve dosyaları incelendi. Geliş şikayetleri, muayene bulguları ve altta yatan etiyolojiye göre bulgular sınıflandırıldı. Bulgular: Çalışmaya alınan hastaların 20 'si erkek, 48 'si kadındı. Yaş ortalamaları 41.88i18.68'di. Hastalar en sık başağrısı, bulantı, kusma, görmede bulanıklık, nöbet geçirme şikayeti ile başvurmuşlardır. Nörolojik muayenede en sık görülen bulgu papiI ödemdir. Manyetik rezonans venografide tromboz, en sık transvers sinus ve sigmoid sinüste görülmüştür. Etiyolojide protein eksikliği, protein eksikliği, protein rezistansı, gebelik, puerperium, oral kontraseptif kullanımı, mastoidit, sinüzit, Behçet hastalığı, akciğer kanseri, beyin tümörü, meme kanseri, kafa travması, beyin cerrahide tümör operasyonu ve hiperho-- mosistinemi saptanmış olup 17 hastanın sinus ven trombozu etiyolojisi idiopatik olarak değerlendirilmiştir. Sonuç: Özellikle başağrısı şikayeti ile gelen genç kadın hastalarda sinüs ven trombozu tanısı akla gelmeli, protrombotik durumlar dışındaki etiyolojiler de araştırılmalıdır.

Serebral Sinus Venöz Trombozlu HastalarÖn Deþerlendirilmesi

Aim: Thrombosis of the dural sinus and/or cerebral veins (CVT) is an uncommon form of stroke, usually affecting young individuals and represents 0.5% to 1% of all strokes. Predisposing causes of CVT are multiple. The aim of our study was to evaluate the patients who were diagnosed sinus vein thrombosis at our clinic and discuss the underlying etiology, age and sex distribution , clinical and imaging findings. Material and Methods: Between January 2005 and January 2015, the records of 68 patients who were hospitalized at Neurology clinic for etiological assesment were collected from hospital records and files. Complaints, examination findings and underlying etiologies were classified. Results: A total of 68 patients ( 20 male, 48 female) were enrolled to the study. Mean age was 41.88±18.68. Patients’ most commonly complaints were headache, nausea, vomiting , blurred vision and seizures. Papilledema was the most common finding on neurologic examination. Thrombosis was observed most frequently in the transverse sinus and sigmoid sinus on magnetic resonance venography. For the etiology, protein C deficiency, protein S deficiency, protein C resistance, pregnancy, puerperium, oral contraceptive usage, mastoiditis, sinusitis, Behcet's disease, lung cancer, brain tumors, breast cancer, head trauma, brain surgery, tumor surgery and hyperhomocysteinemia were identified. Seventeen patients with sinus venous thrombosis were considered with idiopathic etiology. Conclusion: Especially for the young female patients with headache sinus venous thrombosis should be considered. Beside the protrombotic conditions other etiologies should be investigated

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