Halil ÖZDEMİR, Ergin ÇİFTÇİ, Ülker DOĞRU, E. Bahar BİNGÖLER, Erdal İNCE

Kızıl ile ilişkili hepatit

Çocuklarda akut tonsillofarenjitin en yaygın bakteriyel etkeni A grubu beta hemolitik streptokoktur. Eritrojenik eksotoksinler üreten A grubu beta hemolitik streptokok suşları kızıl olarak bilinen tipik bir döküntülü hastalık oluşturur. Burada kızıl ile birlikte hepatiti olan iki çocuk hasta sunulmuştur. Hastalar ateş, döküntü karın ağrısı ve koyu renkli idrar çıkarma yakınmaları ile başvurmuştur. Karaciğer transaminazlarında yükselme saptanan hastalarda hepatit yapan viruslar gösterilememiştir. Her iki hastanın boğaz kültüründe A grubu beta hemolitik streptokok üremiştir. Benzatin penisilin tedavisi ile hastaların tüm klinik ve laboratuvar bulguları gerilemiştir. A grubu beta hemolitik streptokok enfeksiyonlarında hepatit gelişebileceği göz ardı edilmemelidir.

Scarlet fever associated with hepatitis

The most common cause of tonsillopharyngitis is group A beta hemolytic streptococcus in children. Group A beta hemolytic streptococcus strains producing erythrogenic exotoxins are caused a typical exanthematous diseases called as scarlet fever. In this report, two children with scarlet fever associated with hepatitis have presented. Patient complained with fever, rash, abdominal pain, and dark urine. Hepatitis producing viruses couldn't demonstrated in patients who has elevated hepatic transaminases. Group A beta hemolytic streptococci were isolated from throat cultures of both patients. All clinical and laboratory findings of the patients were recovered by benzathine penicillin treatment. Hepatitis should not be overlooked in patients with group A beta hemolytic streptococcal infections.

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