Emine ÇÖLGEÇEN, Ali Rıza ERBAY, Mustafa Fatih ERKOÇ, Hüseyin EDE, Yurdanur AKYÜZ

Correlation of Carotid Intima Media Thickness and Aortic Stiffness Index With Androgenetic Alopecia

Amaç: Androgenetik alopezi (AGA), hem erkeklerde hem de kadınlarda genetic yatkınlık varlığında androgenlerin etkisiyle saç kaybı ile giden yaygın bir sağlık sorunudur. Yeni çalı?malar AGA'lı hastalarda artmı? koroner arter hastalığı riski ile ili?kili olduğunu göstermi?tir. Aortik sertlik indeksi (ASİ) ve karotid intima media kalınlığı (KİMK) ateroskeroz varlığı için güçlü belirteçler olarak kabul edilir. Bu çalı?manın amacı, AGA varlığında ASİ ve KİMK arasındaki olası ili?kiyi belirlemektir. Gereç ve Yöntem: Her hangi bir kronik hastalığı olmayan 18-55 ya? arası toplam 159 asemptomatik AGA hastası çalı?maya dahil edildi. Hastaların Hamilton skalasına göre AGA seviyeleri grup I (seviye 1 ve 2) (n=49); grup II ve grup III (seviye 6) olarak sınıflandırıldı. ASİ ve aortik distensibilite (AD) parametreleri ile değerlendirilen aortun elastik özelliklerini belirlemek için ekokardiyografi kullanıldı. KİMK, renkli Doppler ultrasonografi kullanılarak ölçüldü. ASİ, AD ve ortalama KİMK hesaplandı. Hastaların metabolik profillerini ve antropometrik ölçümlerini içeren veriler kaydedildi. Bulgular: Gruplar arasında ya?, boy, vücut kitle indeksi ve sol ventrikül ejeksiyon fraksiyonu açısından anlamlı fark saptanmadı. İstatiksel olarak III. grubun ortalama ASİ, KİMK ve sistolik kan basıncı değerleri I. ve II. gruba nazaran daha yüksekti (her üç parametre için p

Andogenetik Alopesililerde Karotid İntima Media Kalınlığı Ve Aortik Sertlik İndeksi İlișkisi

Aim: Androgenetic alopecia (AGA) is a common health problem which is well associated with hair loss in both male and female subjects by the effect of androgens under the presence of genetic predisposition. Recent studies showed that there is an increased risk for coronary artery disease in AGA patients. The aortic stiffness index (ASI) and the carotid intima media thickness (CIMT) are accepted as a strong marker for the presence of atherosclerosis. The aim of this study is to determine the possible correlation of CIMT and ASI with presence of AGA. Materials and methods: A total of 159 male asymptomatic AGA patients between 18-55 years old without any history of chronic disease enrolled to the study. Patients were classified in the means of their AGA stage as group I (n=49), group II (n=71) and group III (stage 6) (n=39) according to the Hamilton scale. Echocardiography was used to determine the elastic properties of aorta assessed by ASI and aortic distensibility (AD) parameters. CIMT was measured by color Doppler ultrasonography. ASI, AD and mean CIMT were calculated. The data including the patient’s metabolic profile and anthropometric measurements were recorded. Results: There was no significant difference between the groups in the means of age, height, body mass index, and left ventricle ejection fraction. The values of mean ASI, CIMT and systolic blood pressures were significantly higher in group III than group I and group II statistically (p

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