Meral TORUN, Aymelek GÖNENÇ, Cengiz KARDEŞ

Relationship of cigarette smoking with serum lipids and blood pressure in Turkish adults

Çalışmanın amacı Türk Erişkinlerinde sigaranın serum lipidleri ve kan basıncı üzerine olan etkilerini araştırmaktır. Serum total kolesterol, HDL-kolesterol, sigara ve kan basıncı koroner kalp hastalığı için en önemli risk faktörleri olarak kabul edilmektedir. Gelişmekte olan bir ülke olarak Türkiye yüksek kardiovasküler morbidite ve mortalileve sahiptir. Çalışmada sigara ile serum lipidleri ve kan basma arasındaki ilişki İç Anadolu bölgesindeki 25-75 yaşları arasındaki kadın ve erkek 301 kişiden oluşan pilot çalışma ile araştırılmıştır. 80 kişi koroner kalp hastası ve kalan 221 kişi sağlıklı idi. Serum lipid düzeyleri enzimatik olarak ölçülmüştür. Serum lipid düzeyleri üzerine sigaranın etkisi sigara içenler (n=53), sigarayı bırakanlar (n=24) ve sigara içmeyenler (n—224) karşılaştırılmak suretiyle değerlendirilmiştir. Sigara içen grubun serum total kolesterol düzeyleri diğer gruplara göre daha yüksekti, fakat anlamlı bir farklılık yoktu (p>0.05). Serum HDL-kolesterol, LDL-kolesterol, trigliserid ve kan basıncı düzeyleri açısından sigara içen, sigarayı bırakan ve sigara içmeyen gruplarda istatistiksel olarak anlamlı bir farklılık bulunmadı (P>0.05). Serum lipid profiline yaşın, cinsiyetin, kalp hastalığı olmasının veya olmamasının, kuetelet indeksinin (kg/m2) ve beslenme alışkanlığının etkisi de istatistiksel olarak araştırılmıştır. Yaşa göre kan basıncı (sistolik ve diyastolik) karşılaştırıldığında, kan basıncı genç erişkinlerde (45 yaşın altı) 45 yaşın üstündeki erişkinlere göre daha düşük bulunmuştur (p

Türk erişkinlerinde sigara ile serum lipidleri ve kan basıncı arasındaki ilişki

The purpose of the study was to assess the effects of smoking on serum lipids and blood pressure in Turkish Adults. Serum total cholesterol, HDL-cholesterol, smoking arid blood pressure are established as major risk factors for coronary heart disease. Turkey, a developing country, has a high cardiovascular morbidity and mortality, despite low levels of plasma cholesterol. The relations between smoking, serum lipids and blood pressure was examined in pilot study of 301 women and men aged 25 to 75 years from Middle Region of Anatolia (Aksaray-Ortaköy). Eighty individuals has coronary heart disease and the other 221 subjects were healthy. Serum lipid levels were measured enzymatically. The impact of cigarette smoking on serum lipid levels was assessed by comparing smokers (n=53), ex-smokers (n—24) and non-smokers (n=224). Serum total cholesterol levels in smoker's group was higher than those of the other groups, but differences were insignificant (p>0.05). Serum HDL-cholesterol, LDL-cholesterol, triglyceride and blood pressure levels were not statistically different between smoker, ex-smoker and non-smoker groups (p>0.05). Effect of age, sex, presence of heart disease or not, quetelet index (kg/m2), and nutritional habits on the serum lipid profile were also statistically investigated. When blood pressure (systolic and diastolic) was compared according to age, blood pressure in young people (under 45) was found lower than that of people who are above 45 years old (p

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