Pimekrolimus’un Kullanıldığı Bir Vitiligo Olgusu

Özet: Vitiligo; melanin pigmentinin kaybı sonucu deride beyazde pigmente yamalı plakların oluştuğu bir deri hastalığıdır. Klasik tedavi, topikal steroidler, fototerapi ve fotokemoterapiyi içerir. Askomisinden derive pimekrolimus, immunomodülatör makrolaktamlardan yeni bir sınıftır ve özellikle inflamatuvar deri hastalıklarının tedavisi için geliştirilmiştir. Topikal olarak uygulanan pimekrolimus düşük sistemi kabsorbsiyona sahiptir ve yan etkiler kullanım bölgesinde yanma hissinden ibarettir. Bu haliyle steroidlere iyi bir alternatif gibi durmaktadır. Burada, pimekrolimusla tedavi edilen bir vitiligo olgusu sunulmuştur.

Anahtar Kelimeler:

Vitiligo, topikal, pimekrolimus

A Case Of Vitiligo, Treated With Pimecrolimus

Vitiligo is a skin disease characterized with loss of normal pigments and with white depigmented patchy plaques. Classical ways of therapy are topical corticosteroids, phototherapy and photochemotherapy. Pimecrolimus, derivated from ascomisin, is a new class of immunomodulatory macrolactams, and developed for inflammatory skin disease therapy. Side effects are mainly limited to a burning sensation at the application site. It seems a good alternative for steroids. In this case-report, a patient with vitiligo and who is treated with pimekrolimus is presented.

Keywords:

Vitiligo, topical, pimecrolimus,

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