Birinci Karpometakarpal Eklem Osteoartritinin Tedavisi: Kortikosteroid ile Platelet Zengin Plazma –Randomize Karşılaştırmalı Çalışma

Amaç: İleri yaş erkek ve kadınların birinci parmağın karpometakarpal (KMK) eklem artrozu %35,8sıklıkta görülmektedir. Çalışmamızda elde 1. parmak karpometakarpal eklem artrozunda kortikosteroidve platelet zengin plazma (PZP) enjeksiyonunun klinik ve fonksiyonel sonuçlar üzerinde etkisininkarşılaştırılması amaçlanmıştır.Materyal ve Metot: Bu çalışmada Ekim 2016 – Mart 2018 tarihleri arasında kliniğimize başvuran, elde 1.karpometakarpal eklemde osteoartrit tanısı konulan ve daha önce diğer konservatif tedaviyöntemlerinden fayda görmeyen, Eaton‐ Littler sınıflamasına göre evre 2 ve en az 24 hafta takip edilmiş olan 58 hasta prospektif çalışmaya dahil edildi. 1.,2.,3. ve 6. aylarda Dreiser ve VAS skorları iledeğerlendirilerek sonuçlar istatistiksel olarak karşılaştırıldı.Bulgular: Grupların enjeksiyon öncesi VAS ve Dreiser skorları arasında istatistiksel olarak anlamlı farkyoktu (sırası ile p=0,211 ve p=0,239). Her iki grubun kendi içinde enjeksiyon öncesi ile 4.,8.,12. ve 24.haftalardaki klinik skorları arasındaki fark istatistiksel olarak anlamlı olup, VAS ve Dreiser skorlarındadüzelme istatistiksel anlamlı düzeyde olduğu tespit edildi (p

Treatment of the First Carpometacarpal Joint Osteoarthritis: Corticosteroid Versus Platelet Rich Plasma –A Randomized Comparative Study

Objectives: The prevalence of arthrosis of the thumb carpometacarpal (CMC) joint is 35.8% in older males and females. In our study, it was aimed to compare the effect of corticosteroid and platelet‐rich plasma (PRP) injection on the clinical and functional results in arthrosis of the first carpometacarpal joint of the hand. Materials and Methods: 58 patients who presented to our clinic between October 2016 ‐ March 2018 and were diagnosed with osteoarthritis of the first carpometacarpal joint of the hand, who did not previously benefit from other conservative treatment methods, who were stage 2 according to the Eaton‐Littler classification and followed‐up for at least 24 weeks were enrolled in this prospective study. Dreiser and VAS scores at months 1, 2, 3 and 6 were evaluated and the results were statistically compared. Results: There was no statistically significant difference between the groups in terms of pre‐injection VAS and Dreiser scores (p=0.211 and p=0.239, respectively). The difference between the clinical scores before the injection and at weeks 4, 8, 12 and 24 within each group was statistically significant, wherein the improvement in VAS and Dreiser scores was at a statistically significant level (p

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