Murat SADIÇ, Hasan İkbal ATILGAN, Gökhan KOCA, Koray DEMİREL, Aylin BASKIN, Nur AYDINBELGE, Meliha KORKMAZ

YAŞLI POPULASYONUNDA C14 ÜRE NEFES TESTİ İLE HELİCOBACTER PYLORİ ENFEKSİYONU VE DEMOGRAFİK DEĞİŞKENLERİN KARŞILAŞTIRILMASI

AMAÇ: Bu çalışmanın amacı, C14 üre nefes testi ÜNT için başvuran yaşlı hastalarda Helikobakter pilori Hp enfeksiyonunun prevelansını ve Hp prevelansı ile epidemiyolojik, demografik değişkenler arasındaki ilişkiyi araştırmaktı. GEREÇ VE YÖNTEMLER: Çalışmaya nükleer tıp kliniğimize Hp enfeksiyonu için C14 ÜNT uygulanması amacıyla refere edilen 296 yaşlı hasta >65 yaş dahil edildi. Hastalar retrospektif olarak değerlendirildi ve yaş, cinsiyet, kan grubu, geçmiş medikal hikayesi, sigara ve/veya alkol alışkanlığı, yaygın sistemik hastalık bulunması, vücut kitle indeksi VKİ , eğitim seviyesi, evcil hayvan bulunması gibi demografik özelliklere göre gruplandı ve bunlarla Hp pozitifliği arasındaki ilişki değerlendirildi.BULGULAR: Helikobakter pilori prevelansı, bizim yaşlı hasta popülasyonumuzda % 48,9’du. C14 ÜNT sonuçlarının pozitifliğinin değerlendirmesinde istatistiksel anlamlılık bulundu p=0.04 . Pozitif ÜNT ile artan yaş arasında pozitif korelasyon bulundu. Pozitif Hp testi ile cinsiyet, ABO kan grupları, sigara ve/veya alkol alışkanlığı, VKİ değeri, evde evcil hayvan bulunması, ailede herhangi bir gastrik şikayet bulunması arasında istatistiksel anlamlılık saptanmadı p>0,05 . Pozitif test sonuçları ile eğitim seviyesi, yaygın sistemik hastalık bulunması arasında istatistiksel anlamlılık vardı p=0.001 .SONUÇ: Helikobakter pilori pozitifliği ile artan yaş, eğitim seviyesi, yaygın sistemik hastalık bulunması arasında istatistiksel anlamlılık bulduk ve literatürle uyumlu olarak Hp prevelansı ile diğer parametreler arasında anlamlı ilişki yoktu

Anahtar Kelimeler:

C14, H. pilori, Yaşlılık

COMPARISON OF THE HELICOBACTER PYLORI INFECTION WITH C14 UREA BREATH TEST AND DEMOGRAPHIC VARIABLES IN ELDERLY POPULATION

OBJECTIVE: The aim of this study was to investigate the prevalence of Helicobacter pylori Hp infection in elderly patients admitted for C14 urea breath test UBT and the relationship between Hp prevelance and epidemiologic, demographic variables.MATERIAL AND METHODS: The study included 296 elderly patients >65 years who were referred our nuclear medicine department to admit C14 UBT for Hp infection were included in the study. The patients were retrospectively evaluated and grouped according to the age, gender, blood group, past medical history, smoking and/or alcohol habit, presence of common systemic disease, body mass index, demographic properties like educational stage, presence of pet and evaluated the relationship of these properties with Hp positivity.RESULTS: Helicobacter pylori prevalence was 48.9 % in our elderly study population. The statistical significance was found in the evaluation of positivity of C14 UBT result p=0.04 . Positive correlation was found between the positive UBT and increasing age. Statistical significance wasn’t found between the positive Hp test and gender, ABO blood groups, smoking and/or alcohol habit, BMI value, presence of pet at home, any gastric complaints in family p>0.05 . There was statisticial significance between education level, presence of common systemic disease and positive test result p=0.001 .CONCLUSION: We found statistical significance between the Hp positivity and increeasing age, education level, presence of common systemic disease and no significance relationship among Hp prevalence and the other parameters in accordance with the literature

Keywords:

C14, H. pylori, Elderly,

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