SEREBRAL VENÖZ SİNÜS TROMBOZU

Serebral venoz tromboz SVT serebrovasküler hastalıkların nadir görülen bir türüdür. SVT çeşitli belirti ve bulgular ile prezente olabilir. Klinik bulgular baş ağrısı, papilödem, görme kaybı, fokal veya jeneralize nöbetler, fokal nörolojik defisitler, konfüzyon ve koma şeklinde olabilir.Tüm inmelerin yaklaşık %0,5-%1'inden sorumludur. SVT her yaş grubunda görülebilmekle birlikte genellikle genç ve orta yaş hastaları ve daha çok da 20-35 yaş arasındaki kadınları etkilemektedir. Predispozan risk faktörleri hastaların yaklaşık %15'inde tespit edilememektedir. Bu durumun gebelik, puerperium ve oral kontraseptif kullanımı ile ilişkili olduğu düşünülmektedir. Hastalığı erken tanımak ve uygun tedaviyi belirlemek mortalite ve morbiditeyi azaltır

CEREBRAL SINUS VENOUS THROMBOSIS

Cerebral venous thrombosis CVT is a rare form of cerebrovascular disease. It can present with a wide variety of symptoms and signs. Clinical manifestations can include headache, papilledema, visual loss, focal or generalized seizures, focal neurologic deficits, confusion and coma. Cerebral venous thrombosis represents about 0.5% to 1% of all strokes. All age groups can be affected. It often affects young-to-middle-aged patients, and more commonly women between the ages of 20 – 35. Predisposing risk factors cannot be identified in up to 15% of patients. This condition is thought to be associated with pregnancy, puerperium and oral contraseptive use. Early recognition of the disease and determining appropriate treatment reduces mortality and morbidity

___

  • )Bousser MG, Ferro JM. Cerebral venous thrombosis: an upda- te. Lancet neurol. 2007; 6: 162-170.
  • )Stam J. Thrombosis of the cerebral veins and sinuses. N Engl J Med. 2005; 352: 1791-1798.
  • )Lancon JA, Killough KR, Tibbs RE, Lewis AI, Parent AD. Spontaneous dural sinus thrombosis in children. Pediatr Neuro- surg. 1999; 30: 23-9.
  • )N.Y. Barlas, G. Akman-Demir, and S.Z. Bahar. Cerebral Ve- nous Thrombosis in the Mediterranean Area in Adults. Role of Behçet’s Disease as an Underlying Cause. Mediterr J Hematol In- fect Dis. 2011; 3: 2011044.
  • )Saatçi I, Arslan S, Topçu M, Eldem B, Karagöz T, Saatçi U. Case of the month. Eur J Pediatr. 1996; 155: 63-4.
  • )Allroggen H, Abbott RJ. Cerebral venous sinus thrombosis. Postgrad Med J. 2000; 76: 12-15.
  • )Ferro JM, Canhao P, Stam J, et al. Prognosis of cerebral vein and dural sinus thrombosis: results of the International Study on Ce- rebral Vein and Dural Sinus Thrombosis (ISCVT). Stroke. 2004; : 664-670.
  • )Saposnik G, Barinagarrementeria F, Brown RD Jr, et al. Ameri- can heart association Stroke Council and the Council on Epide- miology and Prevention. Diagnosis and management of cerebral venous thrombosis: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2011; 42: 1158-1192.
  • )Kellett MW, Martin PJ, Enevoldson TP, et al. Cerebral venous sinus thrombosis connected with 20210, a mutation of the pro- thanbil gene. J Neurol Neurosurg Psychiatry. 1998; 65: 611-612.
  • )de Bruijn SF, Stam J, Vandenbroucke JP. Increased risk of ce- rebral venous sinus thrombosis with third-generation oral cont- raceptives. Lancet. 1998; 351: 1404.
  • )de Bruijn SF, Stam J, Koopman MM, et al. Case-control study of risk of cerebral sinus thrombosis in oral contraceptive users who are cautious of hereditary prothrombotic conditions. BMJ. ; 316: 589-592. )Cantu C, Barinagarrementeria F. Cerebral venous thrombosis associated with pregnancy and puerperium: review of 67 cases. Stroke. 1993; 24: 1880-1884.
  • )Jeng JS, Tang SC, Yip PK. Incidence and etiologies of stroke during pregnancy and puerperium as evidenced in Taiwanese women.Cerebrovasc Dis. 2004; 18: 290-295.
  • )Dentali F, Gianni M, Crowther MA,et al. Natural history of cerebral vein thrombosis: A systematic review. Blood. 2006; 108: 1134.
  • )Cumurciuc R, Crassard I, Sarov M, et al. Headache as the only neurological sign of cerebral venous thrombosis: a series of 17 cases. J Neurol Neurosurg Psychiatry. 2005; 76: 1084-1087.
  • )Ahn TB, Roh JK. A cave of cortical vein thrombosis with the cord sign. Arch Neurol. 2003; 60: 1314-1316.
  • )Crawford SC, Digre KB, Palmer CA, et al. Thrombosis of the deep venous drainage of the brain in adults. Analysis of 7 cases with review of the literature. Arch Neurol. 1995; 52: 1101-1108.
  • )Wasay M, Bakshi R, Bobustuc G, et al. Cerebral venous th- rombosis: analysis of a multicenter cohort from the United States. J Stroke Cerebrovasc Disord. 2008; 17: 49-54.
  • )Preter M, Tzourio C, Ameri A, et al. Long-term prognosis in cerebral venous thrombosis: follow-up of 77 patients. Stroke. ; 27: 243-246. )Iwashita T, Kitazawa K, Koyama J, et al. Subtle computed tomography abnormalities in cerebral deep sinus thrombosis. J Clin Neurosci. 2007; 14: 68-71.
  • )Leach JL, Fortuna RB, Jones BV, et al. Imaging of cerebral ve- nous thrombosis: Current techniques, spectrum of findings, and diagnostic pitfalls. Radiographics. 2006; 26: S19YS41.
  • )Idbaih A, Boukobza M, Crassard I, et al. MRI of clot in cereb- ral venous thrombosis high diagnostic value of susceptibility-we- ighted images. Stroke. 2006; 37: 991-995.
  • )Provenzale JM, Joseph GJ, Barboriak DP. Dural sinus throm- bosis: Şndings on CT and MRI imaging and diagnostic pitfalls. AJR. 1998; 170: 777-783.
  • )Ozsvath RR, Casey SO, Lunstrin ES, et al. Cerebral venograp- hy: comparison of CT and MR projection venography. AJR Am J Roentgenol. 1997; 169: 1699-1707.
  • )de Bruijn SF, Stam J. Randomized, placebcontrolled trial of anticoagulant treatment with low–molecular-weight heparin for- cerebral sinus thrombosis. Stroke. 1999; 30: 484-488.
  • )Einhaupl K, Stam J, Bousser MG, et al. EFNS guideline on the treatment of cerebral venous and sinus thrombosis in adult pa- tients. Eur J Neurol. 2010; 17: 1229-1235.
  • )Canhao P, Falcao F, Ferro JM. Thrombolytics for cerebral si- nus thrombosis: a systematic review. Cerebrovasc Dis. 2003; 15: 166.
  • )Dentali F, Squizzato A, Gianni M, et al. Safety of thrombolysis in cerebral venous thrombosis: a systematic review of the litera- ture. Thromb Haemost. 2010; 104: 1055-1062.
  • )Ferro JM, Crassard I, Coutinho JM, et al. Decompressive surgery in cerebrovenouthrombosis: a multicenter registry and a systematic review of individual patient data. Stroke. 2011; 42: 2831.
  • )Saadoun D,Wechsler B, Reche-Rigon M, Trad S et al. Cerebral venous thrombosis in Behçet’s disease. Arthritis Rheum. 2009; : 518-26.
  • )Kesler A, Hadayer A, Goldhammer Y,et al. Idiopathic intrac- ranial hypertension: risk of recurrences. Neurology. 2004; 63: 1739.
  • )Masuhr F, Busch M, Amberger N, et al. Risk and predictors of early epileptic seizures in acute cerebral venous and sinus throm- bosis. Eur J Neurol. 2006; 13: 852-856.
Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi-Cover
  • ISSN: 1304-6187
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 2003
  • Yayıncı: Ankara Eğitim ve Araşt. Hast.
Sayıdaki Diğer Makaleler

ANTİTROMBOTİK KULLANAN HASTALARDA REJYONAL ANESTEZİ UYGULAMASI: KLAVUZLAR NE DİYOR ?

Suna AKIN TAKMAZ, ¹ HÜLYA BAŞAR, BÜLENT BALTACI

TEKRARLAYAN TRANSVERS MİYELİT SONRASINDA GELİŞEN NÖROMİYELİTİS OPTİKA

Mehmet İlker YÖN, Selda KESKİN GÜLER, Hafize Nalan GÜNEŞ, Gökçe Burcu ÇOKAL, Cemile SENCER DEMİRCAN, Tahir Kurtuluş YOLDAŞ

ARTROSKOPİK TAMİR ROTATOR KAF YIRTIĞI HASTALARININ TAMAMI İÇİN ALTIN STANDART MIDIR?

Önder ERSAN, Serhan ÜNLÜ, Aytekin AYDIN, Gürkan Yenel BİLGETEKİN, Faruk Mehmet ÇATMA, Alper ÖZTÜRK

NODÜLER SKABİYEZ OLGUSU

Aysun GÖKCE, Müzeyyen GÖNÜL, Bengü ÇEVİRGEN CEMİL, Tuğrul Ahmet SU

YAŞLI POPULASYONUNDA C14 ÜRE NEFES TESTİ İLE HELİCOBACTER PYLORİ ENFEKSİYONU VE DEMOGRAFİK DEĞİŞKENLERİN KARŞILAŞTIRILMASI

Murat SADIÇ, Hasan İkbal ATILGAN, Gökhan KOCA, Koray DEMİREL, Aylin BASKIN, Nur AYDINBELGE, Meliha KORKMAZ

ND-YAG LAZER KAPSÜLOTOMİ SONRASI GLOKOMLU VE SAĞLIKLI GÖZLERDE GÖZ İÇİ BASINCI VE MERKEZİ KORNEA KALINLIĞI DEĞİŞİKLİKLERİ

Ümit EKŞİOĞLU, Evin ŞINGAR, Özgür BALTA, Hande HÜSNİYE TELEK, Firdevs ÖRNEK, Dicle HAZIROLAN, Ayşe BURCU, Mehmet YAKIN

COMPARISON OF THE HELICOBACTER PYLORI INFECTION WITH C14 UREA BREATH TEST AND DEMOGRAPHIC VARIABLES IN ELDERLY POPULATION

Hasan İkbal ATILGAN, Meliha KORKMAZ, Nur AYDINBELGE, Aylin BASKIN, Koray DEMİREL, Gökhan KOCA, Murat SADIÇ

ÇOCUKLUK ÇAĞI MİGRENİNDE PROFİLAKTİK TEDAVİNİN DEĞERLENDİRİLMESİ

Arzu YILMAZ, Gülhis DEDA, Serap TEBER, Ömer BEKTAŞ

İNTRAVASKULER KONTRAST MADDE BİLGİLENDİRME FORMUNUN HASTADA OLUŞTURDUĞU ANKSİYETE DERECESİ VE BUNU ETKİLEYEN FAKTÖRLER

Selma UYSAL RAMADAN, Pınar KOŞAR, Fatma Dilek GÖKHARMAN

SEREBRAL VENÖZ SİNÜS TROMBOZU

Mehmet İlker YÖN, Gökçe Burcu ÇOKAL, Selda Keskin GÜLER