Hüseyin Köseoğlu, Mustafa Tahtacı, Murat Başaran, Samet Yaman, Tevfik Solakoğlu, Öykü Tayfur Yüreklİ, Aylin Demİrezer Bolat, Osman Ersoy

FUNDİK GLAND POLİPLERİ İLE KOLON POLİBİ VEYA KOLOREKTAL KANSER İLİŞKİSİ

Amaç: Fundik gland polip (FGP) olan hastalarda kolorektal kanser ve kolorektal polip sıklığının artıp artmadığına dair çelişkili veriler mevcuttur. Bu çalışmanın amacı ülkemizdeki bir hasta grubunda FGP ile kolorektal neoplaziler arasındaki ilişkiyi ortaya koymaktır. Gereç ve yöntem: Bu çalışma retrospektif olarak yapılmış bir vaka-kontrol çalışmasıdır. Endoskopide FGP saptanan ve yakın zamanda kolonoskopi yapılmış olan hastalar FGP grubu olarak alındı. Endoskopide FGP saptanmayan ve endoskopi yapılan tarihe göre 6 ay içinde kolonoskopi yapılmış olan hastalar kontrol grubu olarak çalışmaya dahil edildi. Bulgular: FGP grubunda 50 ve kontrol grubunda 158 hasta çalışmaya dahil edildi. İki grup kıyaslandığında kolorektal polip sıklığının benzer olduğu izlendi, ancak FGP grubunda kolorektal kanser daha fazla saptandı. Cinsiyete göre alt grup analizi yapıldığında kadınlarda FGP grubunda kolorektal kanser riskinin artmış olduğu izlendi, ancak benzer bir ilişki erkeklerde saptanmamıştır. Sonuç: FGP olan kadın hastalarda kolorektal karsinom sıklığı FGP olmayan kadınlara göre daha fazladır.

THE RELATIONSHIP BETWEEN FUNDIC GLAND POLYP AND COLONIC POLYP OR COLORECTAL CARCINOMA

Purpose: Conflicting results are present whether colorectal carcinomaand colorectal polyps are more frequently detectable in patients withfundic gland polyp (FGP). The aim of this study was to evaluatethe interaction between FGP and colorectal neoplasm in a Turkishpopulation.Materials and methods: A retrospectively analyzed casecontrol study was performed. Patients with FGP who also underwentcolonoscopy recently were classified as the FGP group, and patients whohad no FGP on endoscopy and had a colonoscopy within six monthswere classified as the control group. The colorectal polyp and colorectalcarcinoma prevalence were compared between groups.Results: Fifty patients were included in the FGP group and 158patients in the control group. There was no statistically significantdifference between two groups according to colorectal polyp detection,but colorectal carcinoma was more frequently seen in patients with FGP.When female patients were included in the analysis, patients with FGPhad a higher prevalence for colorectal carcinoma. Similar difference wasnot detected in men.Conclusion: Colorectal carcinoma is more common in femalepatients with FGP compared to female patients without FGP

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