Sertaç GÜLER, Dilber ÜÇÖZ KOCAŞABAN, Sinan ÖZDEMİR

Akut Semptomatik Amitraz Zehirlenmesi

Amitraz tarım ilacı olarak dünyada ve ülkemizde sıklıkla kullanılan bir insektisittir. Amitraz zehirlenmesi nadirdir ve genellikle pediatrik yaş gruplarında görülür. Zehirlenen hastalarda santral sinir sistemi ve solunum depresyonu, hipotansiyon, bradikardi ve hiperglisemi gözlenir. Özgül bir antidotu yoktur ve tedavi semptomatik önlemleri içerir. Biz de burada özkıyım amacıyla bir bardak Kenaz solüsyonu (yaklaşık 100 mL) içen ve hipotansiyon, kusma ve bradikardi ile acil servisimize başvuran 38 yaşında bir erkek hastayı sunuyoruz.

Anahtar Kelimeler:

Amitraz, bradikardi, konfüzyon, acil tıp, hipotansiyon (MeSH Veritabanı).

Acute Symptomatic Amitraz Intoxication

Amitraz is an insecticide that is frequently used as a pesticide in the world and in our country. Amitraz poisoning is rare and usually occurs in pediatric age groups. Central nervous system and respiratory depression, hypotension, bradycardia and hyperglycemia are mainly observed in poisoned patients. There is no specific antidote and treatment includes symptomatic measures. Herein, we report a 38-year-old male patient who ingested a glass of Kenaz solution (about 100 mL) as a suicidal attempt and admitted to our emergency department with hypotension, vomiting, and bradycardia.

Keywords:

Amitraz, bradycardia, confusion, emergency medicine, hypotension,

PDF

___

1.Avsarogullari L, Ikizceli I, Sungur M, Sözüer E, Akdur O, Yücel M. Acute amitraz poisoning in adults: clinical features, laboratory findings, and management. Clin Toxicol (Phila) 2006;44:19-23.
2. Demirel Y, Yilmaz A, Gursoy S, Kaygusuz K, Mimaroglu C. Acute amitraz intoxication: retrospective analysis of 45 cases. Hum Exp Toxicol 2006;25:613-7.
3. Elinav E, Shapira Y, Ofran Y, Hassin T, Ben-Dov IZ. Near-fatal amitraz intoxication: the overlooked pesticide. Basic Clin Pharmacol Toxicol 2005;97:185-7.
4. Eizadi-Mood N, Sabzghabaee AM, Gheshlaghi F, Yaraghi A. Amitraz poisoning treatment: still supportive? Iran J Pharm Res 2011;10:155-8.
5. Gursoy S, Kunt N, Kaygusuz K, Kafali H. Intravenous amitraz poisoning. Clin Toxicol 2005;43:113-16.
6. Jorens PG, Zandijk E, Belmans L, Schepens PJ, Bossaert L. An unusual poisoning with the unusual pesticide amitraz. Hum Exp Toxicol 1997;16:600-601.
7. Doganay Z, Aygun D, Altintop L, Guven H, Bildik F. Basic toxicological approach has been effective in two poisoned patients with amitraz ingestion: case reports. Hum Exp Toxicol 2002;21:55-57.
8. Yaramis A, Soker M, Bilici M. Amitraz poisoning in children. Hum Exp Toxicol 2000;19: 431-33.
9. Ertekin V, Alp H, Selimoglu MA, Karacan M. Amitraz poisoning in children: retrospective analysis of 21 cases. J Int Med Res 2002;30:203-205.
10. Aydin K, Kurtoglu S, Poyrazoglu MH, Uzum K, Ustunbas HB, Hallac IK. Amitraz poisoning in children: clinical and laboratory ﬁndings of eight cases. Hum Exp Toxicol 1997;16:680-82.