Yoğun Bakım Ünitesinde Profilaktik Antibiyotik Kullanımı

Yoğun bakım tedavisi sırasındaki enfeksiyonlar, hekimlere ve hastalara aşılması gereken bir sorun teşkil edegelmiştir. Bu enfeksiyonlar morbidite ve mortalite oranlarını önemli ölçüde artırabilir. Ele alınacak ana konulardan biri, yoğun bakım ünitelerinde antibiyotiklerin profilaktik kullanımıdır. Kritik hastalarda enfeksiyonun engellenmesinin önemi hem morbidite hem de mortaliteyi azaltma potansiyeline dayanmaktadır. Bu azalma ile direnç gelişiminin önlenmesi arasındaki ilişki net değildir. Enfeksiyonlar ayrıca tedavi masraflarını, hastanede kalış süresini ve hastaların prognozunu etkileyebilir. Bu derlemenin amacı, profilaktik antibiyotik kullanımı, yoğun bakım ünitelerinde enfeksiyonların önlenmesi ve antibiyotik direncini en aza indirgeme hususundaki konuları özetlemektir.

Prophylactic Use of Antibiotics in the Intensive Care Unit

Infections during the intensive care treatment present a great continuous challenge to the physicians and to the patients. These infections can significantly increase the morbidity and mortality.One of the major issues to be addressed is the prophylactic use of antibiotics in intensive careunits. The importance of infection prevention in critically ill patients is therefore based on itspotential to reduce both morbidity and mortality. The relationship between this reduction and theprevention of the development of resistance remains unclear. The infections can also affect treatment costs, hospital stay, and patients’ prognosis. This review tends to summarize all the topicsregarding the prophylactic use of antibiotics, prevention of infections in intensive care units, andminimizing the resistance.

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