Alper YOSUNKAYA, Tülay AYDEMİR, Aybars TAVLAN, Jale ÇELİK, Şeref OTELCİOĞLU

Pediyatrik hastalarda halotan ve sevofluran anestezilerinin derlenme üzerine etkileri

Çalışmamızda; pediyatrik anestezide uzun yıllardır tek ajan olarak kullanılan halotan ile son zamanlarda halotana iyi bir alternatif olarak gösterilen sevofluranın derlenme özelliklerini karşılaştırmayı amaçladık. Çalışma fakülte etik kurul izni ve ailelerin onayı alınan, elektif operasyon uygulanacak, 1-6 yaşlarında, ASA I-II grubundan 80 çocuk olguda gerçekleştirildi. Premedikasyon uygulanmayan olgular rastgele iki eşit gruba ayrılarak, I. grupta halotan, II. grupta sevofluran uygulandı. Anestezi indüksiyonu; %50 N2O/O2 karışımı içinde, kirpik refleksi kayboluncaya kadar Grup I' de halotan %0.5 konsantrasyonla başlanıp, her 3-4 nefeste bir %0.5 artırılıp maksimum %3.5'a çıkarılarak; Grup II'de sevofluran %1 konsantrasyonla başlanıp her 3-4 nefeste bir %1-1.5 artırılıp maksimum %7'e çıkarılarak sağlandı. Anestezi idamesi; %50 N2O/O2 karışımı içinde % 1-1.5 halotan veya %3-4 sevofluran ile gerçekleştirildi. Operasyon süresince olguların hemodinamik verileri ve anestezik gazların kesilmesinden sonra olguların ekstübasyon, uyanma ve Aldrete derlenme süreleri kaydedildi. Her iki grubun sistolik ve diyastolik arter basınçları operasyon süresince benzerdi. Kalp atım hızı 10.dk'dan sonra sevofluran grubunda daha yüksek seyretti (p

Anahtar Kelimeler:

Halotan, Anesteziden uyanma dönemi, Çocuk, okul öncesi, Cerrahi işlemler, elektif, Pediatri, Anestezi, inhalasyon, Premedikasyon

Effects of halothane and sevoflurane anesthesia on recovery in pediatric patients

In this study, we aimed to compare the recovery characteristics of halothane which has been almost used as a unique drug in pediatric anesthesia for long y ears and sevoflurane which has been recently put forward as a good alternative to halothane. This study was performed on eighty children scheduled to undergo elective surgery, aged between 1 to 6 years from ASA I-II class after obtaining approval of Faculty Ethic Committee and parents. None of the patients were premedicated. Patients were randomly assigned to two equal groups: Group I, halothane; Group II, sevoflurane. Anesthesia induction was achieved with in 50% N2O/O2 in group I, starting with halothane 0.5% concentration, increasing by 0.5% and reaching to 3.5% maximum, in group II, starting with sevoflurane 1% concentration, increasing by 1-1.5% and reaching to 7% maximum concentration. The maintenance of anesthesia was provided with 50% N2O/O2 in 1-1,5% halothane and 3-4%, sevoflurane. Hemodynamic data during the operation, time of extubation, time of recovery and duration of reaching 8 value of Aldrete score after discontinuation of anesthesia were recorded. There were no differences in systolic and diastolic blood pressures between two groups during operation. Heart rate was higher with sevoflurane than halothane from 10 minutes after intubation till the end of operation (p<0.05). Time of extubation, time of recovery and duration of reaching 8 value of Aldrete score after discontinuation of anesthesia were lower in the sevoflurane group when compared with the children in the halothane group (p<0.05). In conclusion, sevoflurane is a good alternative to halothane in pediatric patients. We concluded that sevoflurane could be preferred to halothane in outpatient anesthesia especially at pediatric age groups .

Keywords:

Halothane, Anesthesia Recovery Period, Child, Preschool, Surgical Procedures, Elective, Pediatrics, Anesthesia, Inhalation, Premedication,

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