OTONOM SİNİR SİSTEMİ VE ANESTEZİ

Otonom sinir sistemi temel olarak spinal kord, beyin sap ve hipotalamusta yer alan merkezler tarafndan aktive edilir. Homeostazisin devam ettirilmesinde önemli bir rol oynamaktadr. Efferent otonomik sinyaller vücudun çeflitli organlarna sempatik ve parasempatik sinir sistemi olarak adlandrlan 2 major alt ünite tarafndan iletilir. Her iki sistemin akti f olarak çalflmas sonucu doku aktivitesi artrlr yada inhibe edilir. Sonuçta doku fonksiyonlarnn do¤ru biçimde regülasyonu korunur. Anestezi uygulamalarnda kullanlan gerek volatil gerekse de intravenöz ajanlar sempatik ve parasempatik sistem üzerine farkl etkiler oluflturmaktadr. Bu derlemenin amac otonom sinir sistemi fizyolojisi ile anestezi prati¤inde uygulanan ilaçlarn bu sistem üzerine etkilerini gözden geçirmektir

AUTONOMIC NERVOUS SYSTEM AND ANESTHESIA

The autonomic nervous system is principally activated by the centers located in spinal cord, brain stem and hypothalamus. It plays an important role in maintaining the homeostasis. Efferent autonomic signals are transmitted to various organs of the body by two major subunits called the sympathetic and parasympathetic nervous system. Tissue activity is increased or inhibited actively as a result of the functions of these two systems. Eventually the regulation of tissue functions is protected in a correct manner. Both volatile and intravenous agents, used in anesthesia practice, produce di fferent effects on sympathetic and parasympathetic systems. In this study we aim to review the autonomic nervous system physiology and the effects of drugs applied in anesthesia on this system.

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