Kadmiyumun erkek üreme sistemi üzerine etkisi

Üreme sistemi fonksiyonları, hem endojen kaynaklı faktörlerin hem de son zamanlarda giderek artan çevre kirliliği gibi eksojen kaynaklı kimyasal ajanlar nedeniyle daha duyarlı hale gelmiştir. Çevresel kirleticilerin içinde önemli bir yere sahip olan ağır metallere maruziyet, başta üreme sistemi olmak üzere çok farklı sistemlerde istenmeyen etkilere yol açarak büyük sağlık sorunu haline gelmiştir. Günlük yaşantımızda yer alan ağır metallerden olan kadmiyumun üreme sağlığına olan etkileri konusunda bilgi, sınırlı sayıdaki epidemiyolojik ve deneysel çalışmalara dayanmaktadır. Literatüre bakıldığında; kadmiyuma düşük seviyelerde maruz kalınması durumunda erkek fertilitesi (sperm kalitesi ve üreme hormonu düzeyleri) üzerindeki olumsuz etkilerini deneysel ve mesleki araştırmalar tarafından destekleyici kanıtlar göze çarpmakla birlikte, bu konu hakkındaki bilgilerin sınırlı ve yetersizliği dikkat çekmektedir. Kadmiyumun zararlı etkilerinden korunabilmek için, konuyla ilgili deneysel çalışmalara ağırlık verilmeli ve elde edilen bulgular epidemiyolojik araştırmalarda ayrıntılı olarak incelenmelidir. Bu nedenle, bu derlemenin amacı, kadmiyumun erkek üreme sistemi üzerine etkilerine dikkat çekmektir

The effects of cadmium on male reproductive system

Reproductive system functions have become more sensitive due to both endogenous factors and exogenous chemical agents, such as the increasing environmental pollution in recent times. Exposure to heavy metals which have an important place in environmental pollutants, has become a worldwide health problem leading to undesirable effects in many different systems, especially in the reproductive system. In our everyday life, the information on the effects of cadmium exposed from different sources on reproductive health effects are based on a limited number of epidemiological and experimental studies. In the literature, along with supporting experimental and occupational evidence for adverse effects of low levels of cadmium on male fertility (sperm quality and reproductive hormone levels), the limited and inadequate information on this subject is noteworthy. In order to be protected from harmful effects of cadmium, relevant experimental studies should be given weight, and the findings obtained should be examined in detail in epidemiological studies. For this reason, the aim of this review is to draw attention to the effects of cadmium on the male reproductive system

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