Hasan Esat YÜCEL, Kenan GÜÇLÜ, Cahit UÇAR, Selcen DURAN, Naime MERİÇ

Islak Kupa Tedavisinin Oksidatif Stres İndeksi ve Total Anti Oksidan Kapasite Düzeylerine Etkisinin Araştırılması: Pilot Bir Çalışma

Amaç: Islak kupa tedavisi bilinen en eski tedavi yöntemlerinden biridir. Son zamanlarda oksidanları uzaklaştırarak, oksidatif stresi azalttığına dair bazı çalışmalar yapılmıştır. Ancak bu çalışmalar sınırlı sayıdadır. Amacımız ıslak kupa tedavisinin oksidan ve anti-oksidan sistem üzerindeki etkinliğini araştırmaktır.Araçlar ve Yöntem: Çalışmamıza 26 hasta dahil edildi. Islak kupa tedavisinde hemen önce venöz kan örneklemesi yapıldı. Kupa tedavisiyle birlikte kupaya dolan kandan, işlemden hemen sonra ve 14. günde yine venöz kandan örneklemeleri yapıldı. Tüm örnek-lerden total oksidan düzey, total anti-oksidan düzey ve oksidatif stress indeksi düzeyleri çalışılarak karşılaştırılması yapıldı.Bulgular: Kupa kanındaki total oksidan düzey, total anti-oksidan düzey ve oksidatif stres indeksi seviyeleri, tüm venöz kan parametrelerinden yüksek bulundu. Uygulama sonrası, total oksidan ve total anti-oksidan düzeylerde belirgin bir değişiklik olmazken, oksidatif stres indeksi önemli bir şekilde azalmıştır.Sonuç: Islak kupa tedavisi, oksidatif doku hasarının en önemli göstergesi olan oksidatif stres indexini azaltır. Bu nedenle oksidatif doku hasarıyla ilişkili hastalıkların tedavisinde yer alabilir.

Anahtar Kelimeler:

ıslak kupa tedavisi, oksidatif stres indeksi, total oksidan düzey, total anti-oksidan düzey

Study on the Effect of Wet Cupping Therapy on Oxidative Stres Index and Total Antioxidant Capacity Levels: A Pilot Study

Purpose: Wet cupping treatment is one of the oldest known methods of treatment.Recently, some studies have shown that wet cupping therapy removes oxidants and reduces oxidative stres.However, these studies are limited.The aim of this study is to investigate the effectiveness of wet cupping treatment on oxidant-anti oxidant system. Materials And Methods: Our study consisted of 26 patients. Right before the wet cupping treatment, venous blood samples were collected. During the procedure, samples were collected from the cup blood. Right after the wet cupping treatment venous blood samples were collected again. On the 14th day, the participants were called and venous blood samples were collected. In all of these samples, total oxidant level (TOS), oxidative stress index (OSI) and total antioxidant level (TAS) levels were studied and compared. Results: Total anti-oxidant level, total oxidant level and oxidative stress index levels in cup blood were higher than all venous blood samples. While there was no significant change in TAS and TOS levels after the application, oxidative stress index levels decreased significantly. Conclusions: Wet cupping therapy reduced the oxidative stress index. Key Words:Wet Cupping Treatment, Oxidative Stress Index Total Oxidant Level and Total Anti-Oxidant Level

Keywords:

oxidative stress ındex, wet cupping treatment, total oxidant level, total anti-oxidant level,

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