Neuropathic pain after dental treatment

Baş ve boyun bölgesi vücudun kronik ağrılardan en çok etkilenen bölgesidir. Nöropatik ağrılar, periferal ya da santral sinir siste- mindeki primer bir lezyon, disfonksiyon ya da geçici bir bozukluk sonucu başlayan kronik ağrılardan birisidir. Trigeminal nöralji, atipik odontalji (fantom diş ağrısı), yanan ağız sendromu, travmatik nöropatiler, postherpetik nöralji ve kompleks bölgesel ağrı sendromu diş ve ağrı kliniklerinde karşılaşılabilecek nöpatik orofasial ağrılardandır. Ağız içersinde şikayete neden olan ağrıların bir kısmının nöropatik ağrılar olabileceği hatırlanmadığında yanlış tanı konulmakta ve etkilenen bölgedeki dişlere gereksiz tedaviler yapılmaktadır. Bu yazıda, dental işlemler sonrası ortaya çıkabilen posttravmatik periferal ağrılı nöropatiler tartışıldı.

Dental tedaviler sonrası oluşan nöropatik ağrılar

The head and neck regions are the most common sites of the human body to be involved in chronic pain conditions. Neuro- pathic pain is a chronic pain condition, and refers to all pain initiated or caused by a primary lesion or dysfunction or transi- tory perturbation in the peripheral or central nervous system (CNS). Trigeminal neuralgia, atypical odontalgia (phantom tooth pain), burning mouth syndrome, traumatic neuropathies, postherpetic neuralgias and complex regional pain syndrome are neuropathic pain conditions in the orofacial region that can be encountered in pain and dental clinics. The majority of the time this problem is misdiagnosed by the dentist, which can lead to unnecessary treatments. These treatments may include endodontic treatment and extraction of the tooth or teeth in the region. In this review, only post-traumatic peripheral pain neuropathies seen after dental treatments will be discussed.

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  • 1. Merskey H. Pain terms: a list with definitions and notes on usage. Recommended by the IASP Subcommittee on Tax- onomy. Pain 1979;6(3):249.
  • 2. Donaldson D, Kroening R. Recognition and treatment of patients with chronic orofacial pain. J Am Dent Assoc 1979;99(6):961-6.
  • 3. Spencer CJ, Gremillion HA. Neuropathic orofacial pain: proposed mechanisms, diagnosis, and treatment consider- ations. Dent Clin North Am 2007;51(1):209-24.
  • 4. Merskey H, Bogduk N. Classification of chronic pain. 2nd ed. Seattle: IASP Press; 1994.
  • 5. Terminology., IASP (International Association for the Study of Pain) IASP painhttp://www.halcyon.com/iasp/terms-p. html.
  • 6. Vadalouca A, Siafaka I, Argyra E, Vrachnou E, Moka E. Thera- peutic management of chronic neuropathic pain: an ex- amination of pharmacologic treatment. Ann N Y Acad Sci 2006;1088:164-86.
  • 7. De Leeuw R. Orofacial pain: guidelines for assessment, diag- nosis and management. 4th ed. American Academy of Oro- facial Pain. Chicago, IL: Quintessence Books; 2008.
  • 8. Okeson JP. Bell’s orofacial pains. 5th ed., Chicago Ill: Quintes- sence Pub; 1995. p. 74-5.
  • 9. Benoliel R, Eliav E. Neuropathic orofacial pain. Oral Maxillofac Surg Clin North Am 2008;20(2):237-54, vii.
  • 10. Woolf CJ, Mannion RJ. Neuropathic pain: aetiology, symptoms, mechanisms, and management. Lancet 1999;353(9168):1959-64.
  • 11. Beniczky S, Tajti J, Tímea Varga E, Vécsei L. Evidence-based pharmacological treatment of neuropathic pain syndromes. J Neural Transm 2005;112(6):735-49.
  • 12. Benoliel R, Sharav Y. Chronic orofacial pain. Curr Pain Head- ache Rep 2010;14(1):33-40.
  • 13. Devor M. Sodium channels and mechanisms of neuropathic pain. J Pain 2006;7(1 Suppl 1):S3-S12.
  • 14. Lund JP, Lavigne GJ, Dubner R, Sessle BJ. Orofacial pain from basic science to clinical management. Quintessence Books, USA: 2001.
  • 15. Attal N, Bouhassira D. Mechanisms of pain in peripheral neu- ropathy. Acta Neurol Scand Suppl 1999;173:12-24.
  • 16. Fried K, Bongenhielm U, Boissonade FM, Robinson PP. Nerve injury-induced pain in the trigeminal system. Neuroscientist 2001;7(2):155-65.
  • 17. Sessle BJ. Acute and chronic craniofacial pain: brainstem mechanisms of nociceptive transmission and neuroplas- ticity, and their clinical correlates. Crit Rev Oral Biol Med 2000;11(1):57-91.
  • 18. Lewis MA, Sankar V, De Laat A, Benoliel R. Management of neuropathic orofacial pain. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;103 Suppl:S32.e1-24.
  • 19. Jensen TS, Baron R. Translation of symptoms and signs into mechanisms in neuropathic pain. Pain 2003;102(1-2):1-8.
  • 20. Osterberg A, Boivie J, Holmgren H, Thuomas K-A, Johans- son I. The clinical characteristics and sensory abnormalities of patients with central pain caused by multiple sclerosis. In: Gebhart GF, Hammond DL, Jensen TS, editors. Progress in pain research and management. Seattle: IASP Press; 1994. p. 789-96.
  • 21. Misch CE, Resnik R. Mandibular nerve neurosensory impair- ment after dental implant surgery: management and proto- col. Implant Dent 2010;19(5):378-86.
  • 22. Bennett GJ. Neuropathic pain in the orofacial region: clinical and research challenges. J Orofac Pain 2004;18(4):281-6.
  • 23. Eliav E, Gracely RH, Nahlieli O, Benoliel R. Quantitative senso- ry testing in trigeminal nerve damage assessment. J Orofac Pain 2004;18(4):339-44.
  • 24. Jääskeläinen SK. The utility of clinical neurophysiological and quantitative sensory testing for trigeminal neuropathy. J Orofac Pain 2004;18(4):355-9.
  • 25. Waldram M. Peripheral nerve injuries. Trauma 2003;5:79.
  • 26. Evans GR. Peripheral nerve injury: a review and approach to tissue engineered constructs. Anat Rec 2001;263(4):396-404.
  • 27. Flores AJ, Lavernia CJ, Owens PW. Anatomy and physiology of peripheral nerve injury and repair. Am J Orthop (Belle Mead NJ) 2000;29(3):167-73.
  • 28. Seddon JJ. Three types of nerve injury. Brain 1943;66:237-40.
  • 29. Sunderland S. A classification of peripheral nerve injuries produced by a loss of function. Brain 1952;74:491-505.
  • 30. Birch R, Giddins G. 1998. Peripheral nerve injuries.In: Foy, Fagg eds. Medicolegal reportingin orthopaedic trauma. Ed- inburgh: Churchill Livingstone.
  • 31. Zakrzewska JM. Classification issues related to neuropathic trigeminal pain. J Orofac Pain 2004;18(4):325-31.
  • 32. Blondeau F, Daniel NG. Extraction of impacted mandibular third molars: postoperative complications and their risk fac- tors. J Can Dent Assoc 2007;73(4):325.
  • 33. Valmaseda-Castellón E, Berini-Aytés L, Gay-Escoda C. Infe- rior alveolar nerve damage after lower third molar surgi- cal extraction: a prospective study of 1117 surgical extrac- tions. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001;92(4):377-83.
  • 34. Renton T, Hankins M, Sproate C, McGurk M. A randomised controlled clinical trial to compare the incidence of injury to the inferior alveolar nerve as a result of coronectomy and re- moval of mandibular third molars. Br J Oral Maxillofac Surg 2005;43(1):7-12.
  • 35. Loescher AR, Smith KG, Robinson PP. Nerve damage and third molar removal. Dent Update 2003;30(7):375-80, 382.
  • 36. Benediktsdóttir IS, Wenzel A, Petersen JK, Hintze H. Mandib- ular third molar removal: risk indicators for extended opera- tion time, postoperative pain, and complications. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004;97(4):438-46.
  • 37. Ellies LG, Hawker PB. The prevalence of altered sensation as- sociated with implant surgery. Int J Oral Maxillofac Implants 1993;8(6):674-9.
  • 38. Gregg JM. Neuropathic complications of mandibular implant surgery: review and case presentations. Ann R Australas Coll Dent Surg 2000;15:176-80.
  • 39. Worthington P. Injury to the inferior alveolar nerve during implant placement: a formula for protection of the patient and clinician. Int J Oral Maxillofac Implants 2004;19(5):731-4.
  • 40. Hegedus F, Diecidue RJ. Trigeminal nerve injuries after man- dibular implant placement--practical knowledge for clini- cians. Int J Oral Maxillofac Implants 2006;21(1):111-6.
  • 41. Hillerup S, Jensen R. Nerve injury caused by mandibular block analgesia. Int J Oral Maxillofac Surg 2006;35(5):437-43.
  • 42. Delcanho RE. Neuropathic implications of prosthodontic treatment. J Prosthet Dent 1995;73(2):146-52.
  • 43. Rubenstein JE, Taylor TD. Apical nerve transection resulting from implant placement: a 10-year follow-up report. J Pros- thet Dent 1997;78(6):537-41.
  • 44. Wismeijer D, van Waas MA, Vermeeren JI, Kalk W. Patients’ perception of sensory disturbances of the mental nerve be- fore and after implant surgery: a prospective study of 110 patients. Br J Oral Maxillofac Surg 1997;35(4):254-9.
  • 45. Bartling R, Freeman K, Kraut RA. The incidence of altered sen- sation of the mental nerve after mandibular implant place- ment. J Oral Maxillofac Surg 1999;57(12):1408-12.
  • 46. Walton JN. Altered sensation associated with implants in the anterior mandible: a prospective study. J Prosthet Dent 2000;83(4):443-9.
  • 47. von Arx T, Häfliger J, Chappuis V. Neurosensory disturbances following bone harvesting in the symphysis: a prospective clinical study. Clin Oral Implants Res 2005;16(4):432-9.
  • 48. Renton T. Prevention of iatrogenic inferior alveolar nerve in- juries in relation to dental procedures. SADJ 2010;65(8):342- 4, 346-8, 350-1.
  • 49. Cheung LK, Lo J. The long-term clinical morbidity of mandib- ular step osteotomy. Int J Adult Orthodon Orthognath Surg 2002;17(4):283-90.
  • 50. Walton JN. Altered sensation associated with implants in the anterior mandible: a prospective study. J Prosthet Dent 2000;83(4):443-9.
  • 51. Knowles KI, Jergenson MA, Howard JH. Paresthesia associ- ated with endodontic treatment of mandibular premolars. J Endod 2003;29(11):768-70.
  • 52. Nitzan DW, Stabholz A, Azaz B. Concepts of accidental over- filling and overinstrumentation in the mandibular canal dur- ing root canal treatment. J Endod 1983;9(2):81-5.
  • 53. Fanibunda K, Whitworth J, Steele J. The management of ther- momechanically compacted gutta percha extrusion in the inferior dental canal. Br Dent J 1998;184(7):330-2.
  • 54. Pogrel MA. Damage to the inferior alveolar nerve as the re- sult of root canal therapy. J Am Dent Assoc 2007;138(1):65-9.
  • 55. Polycarpou N, Ng YL, Canavan D, Moles DR, Gulabivala K. Prevalence of persistent pain after endodontic treatment and factors affecting its occurrence in cases with complete radiographic healing. Int Endod J 2005;38(3):169-78.
  • 56. Marbach JJ, Hulbrock J, Hohn C, Segal AG. Incidence of phan- tom tooth pain: an atypical facial neuralgia. Oral Surg Oral Med Oral Pathol 1982;53(2):190-3.
  • 57. Reinhilde J, De Geyseleer C, Van Loven K, De Laat A, Lam- brechts P, van Steenberghe D. Appearance of painful or non- painful phantom tooth after tooth extraction. J Dent Res 1998;77:1008.
  • 58. Campbell RL, Parks KW, Dodds RN. Chronic facial pain as- sociated with endodontic therapy. Oral Surg Oral Med Oral Pathol 1990;69(3):287-90.
  • 59. Pogrel MA, Thamby S. Permanent nerve involvement result- ing from inferior alveolar nerve blocks. J Am Dent Assoc 2000;131(7):901-7.
  • 60. Haas DA, Lennon D. A 21 year retrospective study of reports of paresthesia following local anesthetic administration. J Can Dent Assoc 1995;61(4):319-20, 323-6, 329-30.
  • 61. Smith MH, Lung KE. Nerve injuries after dental injection: a review of the literature. J Can Dent Assoc 2006;72(6):559-64.
  • 62. Behrman S. Facial neuralgias. Br Dent J 1949;86(8):197–203.
  • 63. Jaeger B, Singer E, Kroening R. Reflex sympathetic dystrophy of the face. Report of two cases and a review of the literature. Arch Neurol 1986;43(7):693-5.
  • 64. Saxen MA, Campbell RL. An unusual case of sympathetically maintained facial pain complicated by telangiectasia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1995;79(4):455- 8.
  • 65. Melis M, Zawawi K, al-Badawi E, Lobo Lobo S, Mehta N. Com- plex regional pain syndrome in the head and neck: a review of the literature. J Orofac Pain 2002;16(2):93-104.