Doğum analjezisinde epidural sürekli infüzyon ve hasta kontrollü epidural bolus uygulamasının karşılaştırılması

Amaç: Çalışmamızda vaginal doğumda epidural katater takılarak düşük doz levobupivakain ve fentanil kombinasyonu ile yapılan sürekli infüzyon ve hasta kontrollü bolus uygulamanın anne, bebek ve doğum süreci üzerine etkisini karşılaştırmayı amaçladık. Gereç ve Yöntem: Çalışmaya katılan 45 gebe rastgele Grup HKEB (hasta kontrollü epidural bolus) ve Grup SEİ (sürekli epidural infüzyon) olarak iki gruba ayrıldı. Gebelerin hemodinamik parametreleri ve VAS değerleri, fetal kalp tepe atımı, be- bek APGAR skorları, doğum evrelerinin süreleri, doğum şekilleri ve yan etkiler kaydedildi. T10 dermatoma ulaşma süreleri belirlendi. Motor blokaj düzeyleri modifiye Bromage skalası ile değerlendirildi. Ek analjezik ihtiyaçları takip edildi, toplam ilaç tüketimleri karşılaştırıldı. Bulgular: Hasta kontrollü epidural bolus uygulamada toplam ilaç tüketiminin anlamlı olarak daha az olduğunu görüldü (p

The comparison of epidural continuous infusion and epidural patient controlled bolus administration in labor analgesia

Objectives: We aimed to compare the efficacies of patient controlled bolus administration and continuous infusion of low dose Fen- tanyl and Levobupivacaine combination by epidural catheter during vaginal labor on mother, baby and the duration of labor. Methods: The 45 pregnant women involved in the study were divided randomly into two groups, Group HKEB (patient controlled epidural bolus) and Group SEI (continuous epidural infusion). Hemodynamic parameters and VAS values of the pregnant women, fetal heart rate, Apgar scores, duration of labor stages, types of delivery and side effects were recorded. Time to reach the T10 dermatome was determined. Motor block was evaluated with modified Bromage scale. Additional analgesic needs were followed up and total drug consumptions were compared. Results: Drug consumption was found to be significantly lower in HKEB administration (p<0.01). Conclusion: Bolus administration of a basal dose that will keep the analgesia level constant and additional drugs administered upon patient requests will prevent pregnant women from experiencing a painful period, and will provide confidence and comfort to patients who need to ask for drugs according to their pain characteristics

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  • 1. Littleford J. Effects on the fetus and newborn of mater- nal analgesia and anesthesia: a review. Can J Anaesth 2004;51(6):586-609.
  • 2. Gomar C, Fernandez C. Epidural analgesia-anaesthesia in ob- stetrics. Eur J Anaesthesiol 2000;17(9):542-58.
  • 3. Practice Guidelines for Obstetric Anestesia. An Updated re- port by the American Society of Anesthesiologists Task Force on Obstetric Anesthesia. Anesthesiology 2007;106(4):843- 63.
  • 4. Smedstad KG, Morison DH. A comparative study of continu- ous and intermittent epidural analgesia for labour and deliv- ery. Can J Anaesth 1988;35(3 ( Pt 1)):234-41.
  • 5. Paech MJ. Patient-controlled epidural analgesia in labour- -is a continuous infusion of benefit? Anaesth Intensive Care 1992;20(1):15-20.
  • 6. Boselli E, Debon R, Cimino Y, Rimmelé T, Allaouchiche B, Chassard D. Background infusion is not beneficial during la- bor patient-controlled analgesia with 0.1% ropivacaine plus 0.5 microg/ml sufentanil. Anesthesiology 2004;100(4):968- 72.
  • 7. Missant C, Teunkenst A, Vandermeersch E, Van de Velde M. Patient-controlled epidural analgesia following combined spinal-epidural analgesia in labour: the effects of adding a continuous epidural infusion. Anaesth Intensive Care 2005;33(4):452-6.
  • 8. Ferrante FM, Rosinia FA, Gordon C, Datta S. The role of con- tinuous background infusions in patient-controlled epidural analgesia for labor and delivery. Anesth Analg 1994;79(1):80- 4.
  • 9. Boutros A, Blary S, Bronchard R, Bonnet F. Comparison of in- termittent epidural bolus, continuous epidural infusion and patient controlled-epidural analgesia during labor. Int J Ob- stet Anesth 1999;8(4):236-41.
  • 10. Wong CA, Ratliff JT, Sullivan JT, Scavone BM, Toledo P, Mc- Carthy RJ. A randomized comparison of programmed inter- mittent epidural bolus with continuous epidural infusion for labor analgesia. Anesth Analg 2006;102(3):904-9.
  • 11. Lim Y, Sia AT, Ocampo C. Automated regular boluses for epi- dural analgesia: a comparison with continuous infusion. Int J Obstet Anesth 2005;14(4):305-9.
  • 12. Bremerich DH, Waibel HJ, Mierdl S, Meininger D, Byhahn C, Zwissler BC, et al. Comparison of continuous background infusion plus demand dose and demand-only parturient- controlled epidural analgesia (PCEA) using ropivacaine combined with sufentanil for labor and delivery. Int J Obstet Anesth 2005;14(2):114-20.
  • 13. Lim Y, Ocampo CE, Supandji M, Teoh WH, Sia AT. A random- ized controlled trial of three patient-controlled epidural an- algesia regimens for labor. Anesth Analg 2008;107(6):1968- 72.
  • 14. Power I, Thorburn J. Differential flow from multihole epidural catheters. Anaesthesia 1988;43(10):876-8.
  • 15. Kaynar AM, Shankar KB. Epidural infusion: continuous or bo- lus? Anesth Analg 1999;89(2):534.
  • 16. Hogan Q. Distribution of solution in the epidural space: ex- amination by cryomicrotome section. Reg Anesth Pain Med 2002;27(2):150-6.
  • 17. Chua SM, Sia AT. Automated intermittent epidural boluses improve analgesia induced by intrathecal fentanyl during labour. Can J Anaesth 2004;51(6):581-5.
  • 18. Ueda K, Ueda W, Manabe M. A comparative study of sequen- tial epidural bolus technique and continuous epidural infu- sion. Anesthesiology 2005;103(1):126-9.
  • 19. Stienstra R. Patient-controlled epidural analgesia or con- tinuous infusion: advantages and disadvantages of different modes of delivering epidural analgesia for labour. Curr Opin Anaesthesiol 2000;13(3):253-6.
  • 20. van der Vyver M, Halpern S, Joseph G. Patient-controlled epi- dural analgesia versus continuous infusion for labour anal- gesia: a meta-analysis. Br J Anaesth 2002;89(3):459-65.