Diş Hekimliğinde Zirkonya İmplantlar ve Protetik Uygulamaları

Titanyum implantlar, biyouyumlulukları, üstün mekanik özellikleri ve uzun dönemdeki başarılı sonuçlarıyla implant uygulamalarında altın standart oluşturmaktadır. Fakat estetik beklentilerin yüksek olduğu hastalarda, titanyumun gri renginin dezavantaj oluşturabilmesi diş rengine benzer implant materyallerinin kullanımını gündeme getirmiştir. Zirkonya, yüksek dayanıklılığı, biyouyumluluğu ve estetik özellikleri nedeniyle dental implant materyali olarak alternatif bir tedavi seçeneği oluşturmaktadır. Bu literatür derlemesinin amacı, dental zirkonya implantlar ve protetik uygulamalar hakkında bilgi vermektedir
Anahtar Kelimeler:

Zirkonya, Seramik İmplantlar

Zirconia Implants in Dentistry and Prosthetic Applications

Titanium implants have become a gold standard for dental implant applications because of their welldocumented biocompatibility, mechanical properties and long-term high success rates. Expectations regarding aesthetics, titanium’s grayish color may be a disadvantage. Using tooth colored implant materials have enabled to achieve the natural appearance. Zirconia has been widely used in medical applications and was suggested as an alternative implant material for dental implants because of its biocompatibility, sufficient mechanical and aesthetic properties. The purpose of this literature review is to give information about dental zirconia implants and their prosthetic applications

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  • Depprich R, Zipprich H, Ommerborn M, Naujoks C, Wiesmann HP, Kiattavorncharoen S, Lauer HC, Meyer U, Kübler NR, Handschel J. Osseo- integration of zirconia implants compared with titanium: an in vivo study. Head Face Med. 4: 1-8, 2008.
  • Hoffmann O, Angelov N, Gallez F, Jung RE, We- ber FE. The zirconia implant-bone interface: a preliminary histologic evaluation in rabbits. Int. J. Oral Maxillofac. Implants. 23:691-695, 2008. Jarmar T, Palmquist A, Brånemark R, Hermansson L, Engqvist H, Thomsen P. Technique for prepara- tion and characterization in cross-section of oral titanium implant surfaces using focused ion beam and transmission electron microscopy. J. Biomed. Mater. Res A. 87:1003-1009, 2008.
  • Oliva J, Oliva X, Oliva JD. Five-year success rate of 831 consecutively placed Zirconia dental imp- lants in humans: a comparison of three different rough surfaces. Int. J. Oral Maxillofac. Implants. 25:336-344, 2010. Albrektson T, Sennerby L, Wennerberg A. Sta- te of the art of oral implants. Periodontol. 2000. 47:15-26, 2008. Elias CN, Lima JHC, Valiev R, Meyers M A. Bi- omedical applications of titanium and its alloys. JOM. 60:46-49, 2008.
  • Steinemann SG. Titanium-the material of choice? Periodontol. 2000. 17:7-21, 1998.
  • Oliva J, Oliva X, Oliva JD. One-year follow-up of first consecutive 100 zirconia dental implants in humans: a comparison of 2 different rough sur- faces. Int. J. Oral Maxillofac. Implants; 22: 430- 435, 2007.
  • Silva NR, Coelho PG, Fernandes CA, Navarro JM, Dias RA, Thompson VP. Reliability of one- piece ceramic implant. J. Biomed. Mater. Res. B Appl. Biomater. 88:419-426, 2009.
  • Andreiotelli M, Kohal RJ. Fracture strength of zir- conia implants after artificial aging. Clin. Implant Dent. Relat. Res. 11:158-166, 2009.
  • Heydecke G, Kohal R, Glaser R. Optimal est- hetics in single tooth replacement with the Re- Implant system: A case report. Int. J. Prosthodont. 12:184-189, 1999.
  • Bianco PD, Ducheyne P, Cuckler JM. Local accu- mulation of titanium released from a titanium imp- lant in the absence of wear. J. Biomed. Mater. Res. 31:227-234, 1996.
  • Weingart D, Steinemann S, Schilli W, Strub JR, Hellerich U, Assenmacher J, Simpson J. Titanium deposition in regional lymph nodes after insertion of titanium screw implants in maxillofacial regi- on. Int. J. Oral Maxillofac. Surg. 23:450-452, 1994.
  • Tschernitschek H, Borchers L, Geurtsen W. No- nalloyed titanium as a bioinert metal-a review. Quintessence Int. 36:523-530, 2005. Kohal RJ, Wolkewitz M, Hinze M, Han JS, Bächle M, Butz F. Biomechanical and histological beha- vior of zirconia implants: an experiment in the rat. Clin. Oral Implants Res. 20:333-339, 2009.
  • Andreiotelli M, Wenz HJ, Kohal RJ. Are ceramic implants a viable alternative to titanium implants? A systematic literature review. Clin. Oral Implants Res. 20:32-47, 2009. Sandhaus S. The Cerasand endosseous implant. Actual Odontostomatol: 41:607-626, 1987.
  • Sandhaus S. [Technic and instrumentation of the implant C.B.S. (Cristalline Bone Screw)]. Informatore Odonto-Stomatologico: 4:19-24, [in Italian], 1968.
  • Schulte W. The intraosseous Al2O3 (Frialit) Tü- bingen implant. Developmental status after eight years (1-3). Quintessence Int. 154:1-39, 1984. Schulte W, d’Hoedt B. [13 years of the Tübin- gen implant system made by Frialit. Additional results]. Z Zahnärztl. Implantol. 3:167–172, [in German], 1988.
  • Schulte W, Heimke A. [The Tübinger immediate implant]. Quintessenz. 27:17-23, [in German], 1976.
  • Schulte W, Kleineikenscheidt H, Lindner K, Scha- reyka R. [The Tübingen immediate implant in clinical studies]. Dtsch Zahnarztl Z. 33:348-359, [in German], 1978.
  • Schulte W, Kleineikenscheidt H, Lindner K, Scha- reyka R, Heimke G, Gerlach C et al. [Animal ex- periments on the question of healing around the Tübingen immediate implant]. Dtsch Zahnarztl Z. 33:326-331, [in German], 1978.
  • Müller W, Piesold J, Glien W. Stomatol DDR. [Properties and clinical application of dental imp- lants of Bionit aluminium oxide ceramic];.38:673- 678, [ in German], 1988. Pi implants]. Dtsch Stomatol. 41:128-132, 1991.
  • Brinkmann EL. Ceramic anchor implant as a bridge-end abutment (Brinkmann’s Class II)--report of 10 years’ experience in clinical use]. Quintes- senz. 38:811-818, [in German], 1987.
  • Koth DL, McKinney RV Jr, Davis QB. The single- crystal sapphire endosteal dental implant. A lon- gitudinal human study: one-year results. J. Prost- het. Dent. 50:72-80, 1983.
  • Akagawa Y, Hashimoto M, Kondo N, Satomi K, Takata T, Tsuru H. Initial bone-implant interfaces of submergible and supramergible endosseous single-crystal sapphire implants. J. Prosthet. Dent. 55:96-100, 1986.
  • Akagawa Y, Hashimoto M, Kondo N, Satomi K, Takata T, Tsuru H. Initial bone-implant interfaces of submergible and supramergible endosseous single-crystal sapphire implants. J. Prosthet. Dent. 55:96-100, 1986. Gahlert M, Gudehus T, Eichhorn S, Steinhauser E, Kniha H, Erhardt W. Biomechanical and histo- morphometric comparison between zirconia imp- lants with varying surface textures and a titanium implant in the maxilla of miniature pigs. Clin. Oral Implants Res. 18:662-668, 2007.
  • Kohal RJ, Klaus G, Strub JR. Zirconia-implant- supported all-ceramic crowns withstand long-term load: a pilot investigation. Clin. Oral Implants Res. 17:565-571, 2006.
  • Hisbergues M, Vendeville S, Vendeville P. Zirco- nia: Established facts and perspectives for a bio- material in dental implantology. J. Biomed. Ma- ter. Res. B. Appl. Biomater. 88:519-529, 2009.
  • Depprich R, Zipprich H, Ommerborn M, Mahn E, Lammers L, Handschel J, Naujoks C, Wies- mann HP, Kübler NR, Meyer U. Osseointegration of zirconia implants: an SEM observation of the bone-implant interface. Head Face Med. 4:1-7, 2008.
  • Stadlinger B, Hennig M, Eckelt U, Kuhlisch E, Mai R. Comparison of zirconia and titanium implants after a short healing period. A pilot study in mini- pigs. Int. J. Oral Maxillofac. Surg. 39:585-592, 2010.
  • Piconi C, Maccauro G. Zirconia as a ceramic bi- omaterial. Biomaterials. 20:1-25, 1999.
  • Piconi C, Maccauro G, Muratori F, Brach Del Prever E. Alumina and zirconia ceramics in joint replacements. J. Appl. Biomater. Biomech. 1:19- 32, 2003.
  • Helmer JD, Driskell TD. Research on bioceramics. Symp. on use of ceramics as surgical implants. South. Carolina (USA): Clemson University, 1969.
  • Guazzato M, Albakry M, Ringer SP, Swain MV. Strength, fracture toughness and microstructure of a selection of all ceramic materials. Part 2. Zirconia-based dental ceramics. Dent. Mater. 20: 449-456, 2004.
  • Deville S, Gremillard L, Chevalier J, Fantozzi G. A critical comporison of methods for the determi- nation of the aging sensivity in biomedical grade yttria-stabilized zirconia. J. Biomed. Mater. Res. B Appl. Biomater. 72: 239-245, 2005. Gahlert M, Burtscher D, Grunert I, Kniha H, Ste- inhauser E. Failure analysis of fractured dental zirconia implants. Clin. Oral Implants Res, [Epub ahead of print], 2011.
  • Mellinghoff J. Erste klinische ergebnisse zu den- talen schrauben implantaten aus zirkonoxid. Z Zahnarztl Implantol. 22: 288-293, 2006.
  • Kollar A, Huber S, Mericske E, Mericske-Stern R. Zirconia for teeth and implants: a case series. Int. J. Periodontics Restorative Dent. 28:479-487, 2008.
  • Sollazzo V, Pezzetti F, Scarano A, Piattelli A, Bignozzi CA, Massari L, Brunelli G, Carinci F. Zirconium oxide coating improves implant osse- ointegration in vivo. Dent. Mater. 24:357-361, 2008.
  • Rocchietta I, Fontana F, Addis A, Schupbach P, Simion M. Surface-modified zirconia implants: tissue response in rabbits. Clin. Oral Implants Res. 20:844-850, 2009.
  • Özkurt Z, Kazazoğlu E. Zirconia dental implants: a literature review. J. Oral Implantol. 37:367- 376, 2011.
  • Sennerby L, Dasmah A, Larsson B, Iverhed M. Bone tissue responses to surface-modified zirco- nia implants: A histomorphometric and removal torque study in the rabbit. Clin Implant Dent Relat Res. 7:S13-20, 2005.
  • Kohal RJ, Wolkewitz M, Tsakona A. The effects of cyclic loading and preparation on the fracture strength of zirconium-dioxide implants: an in vitro investigation. Clin. Oral Implants. Res. 22: 808- 814, 2011.
  • Warashina H, Sakano S, Kitamura S, Yamauchi KI, Yamaguchi J, Ishiguro N, Hasegawa Y. Bi- ological reaction to alumina, zirconia, titanium and polyethylene particles implanted onto murine calvaria. Biomaterials. 24:3655–3661, 2003.
  • Degidi M, Artese L, Scarano A, Perrotti V, Gehr- ke P, Piattelli A. Inflammatory infiltrate, micro- vessel density, nitric oxide synthase expression, vascular endothelial growth factor expression, and proliferative activity in peri-implant soft tissu- es around titanium and zirconium oxide healing caps. J. Periodontol. 77:73–80, 2006.
  • Gahlert M, Röhling S, Wieland M, Sprecher CM, Kniha H, Milz S. Osseointegration of zirconia and titanium dental implants: a histological and histomorphometrical study in the maxilla of pigs. Clin. Oral Implants Res. 20:1247-1253, 2009.
  • Wenz HJ, Bartsch J, Wolfart S, Kern M. Osseoin- tegration and clinical success of zirconia dental implants: a systematic review. Int. J. Prosthodont. 21:27-36, 2008.
  • Çaglar A, Bal BT, Karakoca S, Aydın C, Yılmaz H, Sarısoy S. Three-dimensional finite element analysis of titanium and yttrium-stabilized zirco- nium dioxide abutments and implants. Int. J. Oral Maxillofac. Implants. 26:961-969, 2011.
  • Caglar A, Bal BT, Aydin C, Yilmaz H, Ozkan S. Evaluation of stresses occurring on three different zirconia dental implants: three-dimensional fini- te element analysis. Int. J. Oral Maxillofac. Imp- lants. 25: 95-103, 2010.
  • Oliva J, Oliva X, Oliva JD. Zirconia implants and all-ceramic restorations for the esthetic rep- lacement of the maxillary central incisors. Eur. J. Esthet. Dent. 3: 174-185, 2008.
  • Sierraalta M, Razzoog ME. A maxillary anterior partially edentulous space restored with a one- piece zirconia implant fixed partial denture: a clinical report. J. Prosthet. Dent. 101: 354- 358, 2009.
  • Aydin C, Yilmaz H, Ata SO. Single-tooth zirconia implant located in anterior maxilla. A clinical re- port. N Y State Dent. J. 76:30-33, 2010.
  • Oliva X, Oliva J, Oliva JD. Full-mouth oral reha- bilitation in a titanium allergy patient using zirco- nium oxide dental implants and zirconium oxide restorations. A case report from on going clinical study. Eur. J. Esthet. Dent. 5:190-203, 2010. Esposito M, Grusovin MG, Chew YS, Coulthard P, Worthington HV. Interventions for replacing mis- sing teeth: 1- versus 2-stage implant placement. Cochrane Database Syst Rev. 3:CD006698, 2009.
  • Kohal RJ, Finke HC, Klaus G. Stability of prototy- pe two-piece zirconia and titanium implants after artificial aging: an in vitro pilot study. Clin. Imp- lant Dent. Relat. Res. 11:323-329, 2009. Lee J, Sieweke JH, Rodriguez NA, Schüpbach P, Lindström H, Susin C, Wikesjö UM. Evaluation of nano-technology-modified zirconia oral implants: a study in rabbits. J. Clin. Periodontol; 36:610- 617, 2009.
  • Pirker W, Kocher A. Immediate, non-submerged, root-analogue zirconia implant in single tooth rep- lacement. Int. J. Oral Maxillofac. Surg. 37:293- 295, 2008. Pirker W, Wiedemann D, Lidauer A, Kocher AA. Immediate, single stage, truly anatomic zirconia implant in lower molar replacement: a case re- port with 2.5 years follow-up. Int. J. Oral Maxillo- fac. Surg. 40:212-216, 2011.
  • Pirker W, Kocher A. Immediate, non-submerged, root-analogue zirconia implants placed into single-rooted extraction sockets: 2-year follow-up of a clinical study. Int. J. Oral Maxillofac. Surg. 38:1127-1132, 2009.
  • Heydenrijk K, Raghoebar GM, Meijer HJ, Van Der Reijden WA, Van Winkelhoff AJ, Stegenga B. Two-part implants inserted in a one-stage or a two-stage procedure. A prospective comparative study. J. Clin. Periodontol. 29:901-909, 2002.
  • Goiato MC, Pellizzer EP, dos Santos DM, Barão VA, de Carvalho BM, Magro-Filho O et al. Cli- nical viability of immediate loading of dental implants: part I- factors for success. J. Craniofac. Surg. 20:2139-2142, 2009.
  • Salama H, Rose LF, Salama M, Betts NJ. Imme- diate loading of bilaterally splinted titanium root- form implants in fixed prosthodontics--a technique reexamined: two case reports. Int. J. Periodontics Restorative Dent. 15:344-361, 1995.
  • Kohal RJ, Weng D, Bächle M, Strub JR. Loaded custom-made zirconia and titanium implants show similar osseointegration: an animal experiment. J. Periodontol. 75:1262-1268, 2004.
  • Kohal RJ, Klaus G. A zirconia implant-crown system: a case report. Int. J. Periodontics Restora- tive Dent. 24:147-153, 2004.
  • Nevins M, Camelo M, Nevins ML, Schupbach P, Kim DM. Pilot clinical and histologic evaluations of a two-piece zirconia implant. Int. J. Periodon- tics Restorative Dent. 31:157-163, 2011.
  • Hodosh M, Povar M, Shklar G. The dental poly- mer implant concept. J. Prosthet. Dent. 22:371- 380, 1969. Bianchi AE, Bosetti M, Dolci G Jr, Sberna MT, Sanfilippo S, Cannas M. In vitro and in vivo follow-up of titanium transmucosal implants with a zirconia collar. J. Appl. Biomater. Biomech. 2:143-150, 2004
  • Barter S, Stone P, Brägger U. A pilot study to evaluate the success and survival rate of titanium- zirconium implants in partially edentulous patients: results after 24 months of follow-up. Clin. Oral Implants. Res. [Epub ahead of print], 2011.