Hipertermik İntraperitoneal Kemoterapi Uygulaması: Çalışan Güvenliği

Peritoneal yüzey malignitelerin de yeni tedavi yaklaşımı sitoredüktif cerrahi ile birlikte kombine hipertermik intraperitoneal kemoterapi uygulamasıdır. Sitoredüksiyon cerrahi ile tüm makroskopik tümörlerin çıkarılması, Hipertermik İntraperitoneal Kemoterapi (HİPEK) ile de mikroskobik tümör hücrelerinin yok edilmesi amaçlanmaktadır. Bu yöntem, plazma-periton bariyerini kullanarak kemoterapötik ajanların ısı ile birlikte daha yüksek konsantrasyonlarda ve daha az sitotoksik yan etki ile uygulanmasına olanak sağlamaktadır. Ancak işlem esnasında ameliyathane çalışanlarının kemoterapötik ajanlar ile maruziyet riski söz konusudur. Bu derlemede HİPEK işlemi esnasında maruziyet yolları ve çalışanların sağlığını korumaya yönelik güvenlik önlemleri konusunda literatür bilgileri ele alınmıştır.

Anahtar Kelimeler:

Ameliyathane, Çalışan güvenliği, Kemoterapi, HİPEK, Hemşire

Hyperthermic Intraperitoneal Chemotherapy Application: Employee Safety

A new treatment approach for peritoneal surface malignancies is cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy. It is aimed to remove all macroscopic tumors with cytoreduction surgery, and to destroy microscopic tumor cells with Hyperthermic Intraperitoneal Chemotherapy (HIPEC). This method, using the plasma-peritoneal barrier, allows the administration of chemotherapeutic agent at higher concentrations with temperature and with less cytotoxic side effects. However, there is a risk of exposure of operating room workers to chemotherapeutic agent during the procedure. In this review, literature information on exposure routes and safety measures to protect the health of workers during the HIPEC procedure is discussed.

Keywords:

Operating room, Employee safety, Chemotherapy, HIPEC, nursing,

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