Cengiz ERÇİN, Kadriye YILDIZ, Konuralp İLBAY, Gökhan HAROVA, Ethem ALHAN

Bir Ganglionoroma Olgusu

İzole hamartomatoz ganlionöroma son derece nadir tümörlerden biridir. Adrenal bez ve retroperitoneal bölgede izlenmesine karşın en sık arka mediasten yerleşimlidir. Bu hamartomatoz tümörler nadiren malign odaklar (nöroblastomatöz ya da malign sinir kılıfı tümör alanları) içerebilirler. 17 yaşında kız çocukta üst arka mediasten yerleşimli ganglionöroma olgusunun klinik ve morfolojik bulguları sunulmuştur ve son literatürler gözden geçirilerek tartışılmıştır.

Anahtar Kelimeler:

Ganglionöroma, Von Recklinghausen's disease, satellit hücreleri

A Case Of Ganglioneuroma

Isolated hamartomatous ganglioneuromas are extremely rare tumors. Although they may be found in adrenal gland or retroperitoneal region most of the time, they are localized in the posterior mediastineum. These hamartomatous tumors may rarely possess malignant foci (areas of neuroblastomaous or malignant nerve sheath tumour). An isolatPd hamartomatous ganglioneuroma in a 17 years old girl localised at upper posterior mediasteneum is presented with its clinical and morphologic characteristics and is discussed with current literature data.

Keywords:

Ganglioneuroma, VonRecklinghausen's disease, satellite cells,

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Enzinger FM, Weis SW. Soft Tissue Tumors. 3rd Edition. St Louis, Missouri: Mosby-Year Book, Inc;1995.
Geffner Rl, Hassel CM. Ganglioneuroma of the skin. Arch Dermatol. 1986;122:377.
Harkin JC, Reed RJ. Tumours of the Peripheral Nervous System. In: Atlas of Tumour Pathology. 2nd series fascicle 3. Washington DC: Armed Forces Institute of Pathology; 1982:144-149.
Kroese MCS, Rutgers DH, Wils IS, Van Unnik JA, Roholl PJ. The relevance of the DNA index and proliferation rate in the grading of benign and malignant soft tissue tumors. Cancer. 1990;65(8):1782-1788. doi:10.1002/1097-0142(19900415)65:8<1782::AID-CNCR2820650819>3.0.CO;2-I
Lashmer BA. Ganglioneuromatosis of the colon and extensive glycogenic acanthosis in Cowden 's disease. Dig Dis Sci. 1986;31:28.
Özoran Y, Ruacan P, Komsuoolu SP, Özoran A, Aktürk F. A case of ganglioneuroma. Turkish Journal of Pediatrics. 1987;29:135.
Russel DS, Rubinstein LJ. Pathology of Tumours of the Nervous System: Primary Meningeal and Cerebral Sarcomas. London, UK: Butler and Tanner Ltd; 1989.